Protein Wnt-10a
1_MGSAH 6_ PRPWL 11_ RLRPQ 16_ PQPRP 21_ ALWVL 26_ LFFLL 31_ LLAAA 36_ MPRSA 41_ PNDIL 46_ DLRLP 51_ PEPVL 56_ NANTV 61_ CLTLP 66_ GLSRR 71_ QMEVC 76_ VRHPD 81_ VAASA 86_ IQGIQ 91_ IAIHE 96_ CQHQF 101_ RDQRW 106_ NCSSL 111_ ETRNK 116_ IPYES 121_ PIFSR 126_ GFRES 131_ AFAYA 136_ IAAAG 141_ VVHAV 146_ SNACA 151_ LGKLK 156_ ACGCD 161_ ASRRG 166_ DEEAF 171_ RRKLH 176_ RLQLD 181_ ALQRG 186_ KGLSH 191_ GVPEH 196_ PALPT 201_ ASPGL 206_ QDSWE 211_ WGGCS 216_ PDMGF 221_ GERFS 226_ KDFLD 231_ SREPH 236_ RDIHA 241_ RMRLH 246_ NNRVG 251_ RQAVM 256_ ENMRR 261_ KCKCH 266_ GTSGS 271_ CQLKT 276_ CWQVT 281_ PEFRT 286_ VGALL 291_ RSRFH 296_ RATLI 301_ RPHNR 306_ NGGQL 311_ EPGPA 316_ GAPSP 321_ APGAP 326_ GPRRR 331_ ASPAD 336_ LVYFE 341_ KSPDF 346_ CEREP 351_ RLDSA 356_ GTVGR 361_ LCNKS 366_ SAGSD 371_ GCGSM 376_ CCGRG 381_ HNILR 386_ QTRSE 391_ RCHCR 396_ FHWCC 401_ FVVCE 406_ ECRIT 411_EWVSV
1: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Plays a role in normal ectoderm development (PubMed:17847007, PubMed:28589954). Required for normal tooth development (PubMed:17847007, PubMed:28589954, PubMed:29178643). Required for normal postnatal development and maintenance of tongue papillae and sweat ducts (PubMed:28589954). Required for normal proliferation of basal cells in tongue filiform papillae, plantar epithelium and sweat ducts. Required for normal expression of keratins in tongue papillae (By similarity). Required for normal expression of KRT9 in foot plant epithelium (PubMed:28589954). Required for normal hair follicle function (PubMed:28589954)