Linker for activation of T-cells family member 2 (Linker for activation of B-cells) (Membrane-associated adapter molecule) (Non-T-cell activation linker) (Williams-Beuren syndrome chromosomal region 15 protein) (Williams-Beuren syndrome chromosomal region 5 protein)
1_MSSGT 6_ ELLWP 11_ GAALL 16_ VLLGV 21_ AASLC 26_ VRCSR 31_ PGAKR 36_ SEKIY 41_ QQRSL 46_ REDQQ 51_ SFTGS 56_ RTYSL 61_ VGQAW 66_ PGPLA 71_ DMAPT 76_ RKDKL 81_ LQFYP 86_ SLEDP 91_ ASSRY 96_ QNFSK 101_ GSRHG 106_ SEEAY 111_ IDPIA 116_ MEYYN 121_ WGRFS 126_ KPPED 131_ DDANS 136_ YENVL 141_ ICKQK 146_ TTETG 151_ AQQEG 156_ IGGLC 161_ RGDLS 166_ LSLAL 171_ KTGPT 176_ SGLCP 181_ SASPE 186_ EDEES 191_ EDYQN 196_ SASIH 201_ QWRES 206_ RKVMG 211_ QLQRE 216_ ASPGP 221_ VGSPD 226_ EEDGE 231_ PDYVN 236_GEVAA
1: Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2