GDNF family receptor alpha-4 (GDNF receptor alpha-4) (GDNFR-alpha-4) (GFR-alpha-4) (Persephin receptor)
1_MVRCL 6_ GPALL 11_ LLLLL 16_ GSASS 21_ VGGNR 26_ CVDAA 31_ EACTA 36_ DARCQ 41_ RLRSE 46_ YVAQC 51_ LGRAA 56_ QGGCP 61_ RARCR 66_ RALRR 71_ FFARG 76_ PPALT 81_ HALLF 86_ CPCAG 91_ PACAE 96_ RRRQT 101_ FVPSC 106_ AFSGP 111_ GPAPP 116_ SCLEP 121_ LNFCE 126_ RSRVC 131_ RCARA 136_ AAGPW 141_ RGWGR 146_ GLSPA 151_ HRPPA 156_ AQASP 161_ PGLSG 166_ LVHPS 171_ AQRPR 176_ RLPAG 181_ PGRPL 186_ PARLR 191_ GPRGV 196_ PAGTA 201_ VTPNY 206_ VDNVS 211_ ARVAP 216_ WCDCG 221_ ASGNR 226_ REDCE 231_ AFRGL 236_ FTRNR 241_ CLDGA 246_ IQAFA 251_ SGWPP 256_ VLLDQ 261_ LNPQG 266_ DPEHS 271_ LLQVS 276_ STGRA 281_ LERRS 286_ LLSIL 291_PVLAL
1: Receptor for persephin (PSPN), a growth factor that exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons (PubMed:11116144). Acts by binding to its coreceptor, GFRA4, leading to autophosphorylation and activation of the RET receptor (PubMed:11116144). May be important in C-cell development and, in the postnatal development of the adrenal medulla (PubMed:11116144)