Disintegrin and metalloproteinase domain-containing protein 19 (ADAM 19) (EC 3.4.24.-) (Meltrin-beta) (Metalloprotease and disintegrin dendritic antigen marker) (MADDAM)
1_MPGGA 6_ GAARL 11_ CLLAF 16_ ALQPL 21_ RPRAA 26_ REPGW 31_ TRGSE 36_ EGSPK 41_ LQHEL 46_ IIPQW 51_ KTSES 56_ PVREK 61_ HPLKA 66_ ELRVM 71_ AEGRE 76_ LILDL 81_ EKNEQ 86_ LFAPS 91_ YTETH 96_ YTSSG 101_ NPQTT 106_ TRKLE 111_ DHCFY 116_ HGTVR 121_ ETELS 126_ SVTLS 131_ TCRGI 136_ RGLIT 141_ VSSNL 146_ SYVIE 151_ PLPDS 156_ KGQHL 161_ IYRSE 166_ HLKPP 171_ PGNCG 176_ FEHSK 181_ PTTRD 186_ WALQF 191_ TQQTK 196_ KRPRR 201_ MKRED 206_ LNSMK 211_ YVELY 216_ LVADY 221_ LEFQK 226_ NRRDQ 231_ DATKH 236_ KLIEI 241_ ANYVD 246_ KFYRS 251_ LNIRI 256_ ALVGL 261_ EVWTH 266_ GNMCE 271_ VSENP 276_ YSTLW 281_ SFLSW 286_ RRKLL 291_ AQKYH 296_ DNAQL 301_ ITGMS 306_ FHGTT 311_ IGLAP 316_ LMAMC 321_ SVYQS 326_ GGVNM 331_ DHSEN 336_ AIGVA 341_ ATMAH 346_ EMGHN 351_ FGMTH 356_ DSADC 361_ CSASA 366_ ADGGC 371_ IMAAA 376_ TGHPF 381_ PKVFN 386_ GCNRR 391_ ELDRY 396_ LQSGG 401_ GMCLS 406_ NMPDT 411_ RMLYG 416_ GRRCG 421_ NGYLE 426_ DGEEC 431_ DCGEE 436_ EECNN 441_ PCCNA 446_ SNCTL 451_ RPGAE 456_ CAHGS 461_ CCHQC 466_ KLLAP 471_ GTLCR 476_ EQARQ 481_ CDLPE 486_ FCTGK 491_ SPHCP 496_ TNFYQ 501_ MDGTP 506_ CEGGQ 511_ AYCYN 516_ GMCLT 521_ YQEQC 526_ QQLWG 531_ PGARP 536_ APDLC 541_ FEKVN 546_ VAGDT 551_ FGNCG 556_ KDMNG 561_ EHRKC 566_ NMRDA 571_ KCGKI 576_ QCQSS 581_ EARPL 586_ ESNAV 591_ PIDTT 596_ IIMNG 601_ RQIQC 606_ RGTHV 611_ YRGPE 616_ EEGDM 621_ LDPGL 626_ VMTGT 631_ KCGYN 636_ HICFE 641_ GQCRN 646_ TSFFE 651_ TEGCG 656_ KKCNG 661_ HGVCN 666_ NNQNC 671_ HCLPG 676_ WAPPF 681_ CNTPG 686_ HGGSI 691_ DSGPM 696_ PPESV 701_ GPVVA 706_ GVLVA 711_ ILVLA 716_ VLMLM 721_ YYCCR 726_ QNNKL 731_ GQLKP 736_ SALPS 741_ KLRQQ 746_ FSCPF 751_ RVSQN 756_ SGTGH 761_ ANPTF 766_ KLQTP 771_ QGKRK 776_ VINTP 781_ EILRK 786_ PSQPP 791_ PRPPP 796_ DYLRG 801_ GSPPA 806_ PLPAH 811_ LSRAA 816_ RNSPG 821_ PGSQI 826_ ERTES 831_ SRRPP 836_ PSRPI 841_ PPAPN 846_ CIVSQ 851_ DFSRP 856_ RPPQK 861_ ALPAN 866_ PVPGR 871_ RSLPR 876_ PGGAS 881_ PLRPP 886_ GAGPQ 891_ QSRPL 896_ AALAP 901_ KVSPR 906_ EALKV 911_ KAGTR 916_ GLQGG 921_ RCRVE 926_ KTKQF 931_ MLLVV 936_ WTELP 941_ EQKPR 946_AKHSC
1: Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity)