Gene name: MIS12

Uniprot entry:

Q9H081

Protein names:

Protein MIS12 homolog

Protein sequence:

1_MSVDP 6_ MTYEA 11_ QFFGF 16_ TPQTC 21_ MLRIY 26_ IAFQD 31_ YLFEV 36_ MQAVE 41_ QVILK 46_ KLDGI 51_ PDCDI 56_ SPVQI 61_ RKCTE 66_ KFLCF 71_ MKGHF 76_ DNLFS 81_ KMEQL 86_ FLQLI 91_ LRIPS 96_ NILLP 101_ EDKCK 106_ ETPYS 111_ EEDFQ 116_ HLQKE 121_ IEQLQ 126_ EKYKT 131_ ELCTK 136_ QALLA 141_ ELEEQ 146_ KIVQA 151_ KLKQT 156_ LTFFD 161_ ELHNV 166_ GRDHG 171_ TSDFR 176_ ESLVS 181_ LVQNS 186_ RKLQN 191_ IRDNV 196_EKESK

Protein annotations

Protein functions:

1: Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis (PubMed:12515822, PubMed:15502821, PubMed:16585270). Essential for proper kinetochore microtubule attachments (PubMed:23891108)