FXYD domain-containing ion transport regulator 6 (Phosphohippolin)
1_MELVL 6_ VFLCS 11_ LLAPM 16_ VLASA 21_ AEKEK 26_ EMDPF 31_ HYDYQ 36_ TLRIG 41_ GLVFA 46_ VVLFS 51_ VGILL 56_ ILSRR 61_ CKCSF 66_ NQKPR 71_ APGDE 76_ EAQVE 81_ NLITA 86_NATEP
1: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Reduces the apparent affinity for intracellular Na(+) with no change in the apparent affinity for extracellular K(+) (PubMed:33231612). In addition to modulating NKA kinetics, may also function as a regulator of NKA localization to the plasma membrane (By similarity)