Gene name: ATG10

Uniprot entry:

Q9H0Y0

Protein names:

Ubiquitin-like-conjugating enzyme ATG10 (EC 2.3.2.-) (Autophagy-related protein 10) (APG10-like)

Protein sequence:

1_MEEDE 6_ FIGEK 11_ TFQRY 16_ CAEFI 21_ KHSQQ 26_ IGDSW 31_ EWRPS 36_ KDCSD 41_ GYMCK 46_ IHFQI 51_ KNGSV 56_ MSHLG 61_ ASTHG 66_ QTCLP 71_ MEEAF 76_ ELPLD 81_ DCEVI 86_ ETAAA 91_ SEVIK 96_ YEYHV 101_ LYSCS 106_ YQVPV 111_ LYFRA 116_ SFLDG 121_ RPLTL 126_ KDIWE 131_ GVHEC 136_ YKMRL 141_ LQGPW 146_ DTITQ 151_ QEHPI 156_ LGQPF 161_ FVLHP 166_ CKTNE 171_ FMTPV 176_ LKNSQ 181_ KINKN 186_ VNYIT 191_ SWLSI 196_ VGPVV 201_ GLNLP 206_ LSYAK 211_ATSQD

Protein annotations

Protein functions:

1: E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis