Deoxynucleotidyltransferase terminal-interacting protein 1 (Terminal deoxynucleotidyltransferase-interacting factor 1) (TdIF1) (TdT-interacting factor 1)
1_MGATG 6_ DAEQP 11_ RGPSG 16_ AERGG 21_ LELGD 26_ AGAAG 31_ QLVLT 36_ NPWNI 41_ MIKHR 46_ QVQRR 51_ GRRSQ 56_ MTTSF 61_ TDPAI 66_ SMDLL 71_ RAVLQ 76_ PSINE 81_ EIQTV 86_ FNKYM 91_ KFFQK 96_ AALNV 101_ RDNVG 106_ EEVDA 111_ EQLIQ 116_ EACRS 121_ CLEQA 126_ KLLFS 131_ DGEKV 136_ IPRLT 141_ HELPG 146_ IKRGR 151_ QAEEE 156_ CAHRG 161_ SPLPK 166_ KRKGR 171_ PPGHI 176_ LSSDR 181_ AAAGM 186_ VWKPK 191_ SCEPI 196_ RREGP 201_ KWDPA 206_ RLNES 211_ TTFVL 216_ GSRAN 221_ KALGM 226_ GGTRG 231_ RIYIK 236_ HPHLF 241_ KYAAD 246_ PQDKH 251_ WLAEQ 256_ HHMRA 261_ TGGKM 266_ AYLLI 271_ EEDIR 276_ DLAAS 281_ DDYRG 286_ CLDLK 291_ LEELK 296_ SFVLP 301_ SWMVE 306_ KMRKY 311_ METLR 316_ TENEH 321_RAVEA
1: Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro) (PubMed:11473582). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA