Sphingosine 1-phosphate receptor 5 (S1P receptor 5) (S1P5) (Endothelial differentiation G-protein-coupled receptor 8) (Sphingosine 1-phosphate receptor Edg-8) (S1P receptor Edg-8)
1_MESGL 6_ LRPAP 11_ VSEVI 16_ VLHYN 21_ YTGKL 26_ RGARY 31_ QPGAG 36_ LRADA 41_ VVCLA 46_ VCAFI 51_ VLENL 56_ AVLLV 61_ LGRHP 66_ RFHAP 71_ MFLLL 76_ GSLTL 81_ SDLLA 86_ GAAYA 91_ ANILL 96_ SGPLT 101_ LKLSP 106_ ALWFA 111_ REGGV 116_ FVALT 121_ ASVLS 126_ LLAIA 131_ LERSL 136_ TMARR 141_ GPAPV 146_ SSRGR 151_ TLAMA 156_ AAAWG 161_ VSLLL 166_ GLLPA 171_ LGWNC 176_ LGRLD 181_ ACSTV 186_ LPLYA 191_ KAYVL 196_ FCVLA 201_ FVGIL 206_ AAICA 211_ LYARI 216_ YCQVR 221_ ANARR 226_ LPARP 231_ GTAGT 236_ TSTRA 241_ RRKPR 246_ SLALL 251_ RTLSV 256_ VLLAF 261_ VACWG 266_ PLFLL 271_ LLLDV 276_ ACPAR 281_ TCPVL 286_ LQADP 291_ FLGLA 296_ MANSL 301_ LNPII 306_ YTLTN 311_ RDLRH 316_ ALLRL 321_ VCCGR 326_ HSCGR 331_ DPSGS 336_ QQSAS 341_ AAEAS 346_ GGLRR 351_ CLPPG 356_ LDGSF 361_ SGSER 366_ SSPQR 371_ DGLDT 376_ SGSTG 381_ SPGAP 386_ TAART 391_LVSEP
1: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells