Cadherin-23 (Otocadherin)
1_MGRHV 6_ ATSCH 11_ VAWLL 16_ VLISG 21_ CWGQV 26_ NRLPF 31_ FTNHF 36_ FDTYL 41_ LISED 46_ TPVGS 51_ SVTQL 56_ LAQDM 61_ DNDPL 66_ VFGVS 71_ GEEAS 76_ RFFAV 81_ EPDTG 86_ VVWLR 91_ QPLDR 96_ ETKSE 101_ FTVEF 106_ SVSDH 111_ QGVIT 116_ RKVNI 121_ QVGDV 126_ NDNAP 131_ TFHNQ 136_ PYSVR 141_ IPENT 146_ PVGTP 151_ IFIVN 156_ ATDPD 161_ LGAGG 166_ SVLYS 171_ FQPPS 176_ QFFAI 181_ DSARG 186_ IVTVI 191_ RELDY 196_ ETTQA 201_ YQLTV 206_ NATDQ 211_ DKTRP 216_ LSTLA 221_ NLAII 226_ ITDVQ 231_ DMDPI 236_ FINLP 241_ YSTNI 246_ YEHSP 251_ PGTTV 256_ RIITA 261_ IDQDK 266_ GRPRG 271_ IGYTI 276_ VSGNT 281_ NSIFA 286_ LDYIS 291_ GVLTL 296_ NGLLD 301_ RENPL 306_ YSHGF 311_ ILTVK 316_ GTELN 321_ DDRTP 326_ SDATV 331_ TTTFN 336_ ILVID 341_ INDNA 346_ PEFNS 351_ SEYSV 356_ AITEL 361_ AQVGF 366_ ALPLF 371_ IQVVD 376_ KDENL 381_ GLNSM 386_ FEVYL 391_ VGNNS 396_ HHFII 401_ SPTSV 406_ QGKAD 411_ IRIRV 416_ AIPLD 421_ YETVD 426_ RYDFD 431_ LFANE 436_ SVPDH 441_ VGYAK 446_ VKITL 451_ INEND 456_ NRPIF 461_ SQPLY 466_ NISLY 471_ ENVTV 476_ GTSVL 481_ TVLAT 486_ DNDAG 491_ TFGEV 496_ SYFFS 501_ DDPDR 506_ FSLDK 511_ DTGLI 516_ MLIAR 521_ LDYEL 526_ IQRFT 531_ LTIIA 536_ RDGGG 541_ EETTG 546_ RVRIN 551_ VLDVN 556_ DNVPT 561_ FQKDA 566_ YVGAL 571_ RENEP 576_ SVTQL 581_ VRLRA 586_ TDEDS 591_ PPNNQ 596_ ITYSI 601_ VSASA 606_ FGSYF 611_ DISLY 616_ EGYGV 621_ ISVSR 626_ PLDYE 631_ QISNG 636_ LIYLT 641_ VMAMD 646_ AGNPP 651_ LNSTV 656_ PVTIE 661_ VFDEN 666_ DNPPT 671_ FSKPA 676_ YFVSV 681_ VENIM 686_ AGATV 691_ LFLNA 696_ TDLDR 701_ SREYG 706_ QESII 711_ YSLEG 716_ STQFR 721_ INARS 726_ GEITT 731_ TSLLD 736_ RETKS 741_ EYILI 746_ VRAVD 751_ GGVGH 756_ NQKTG 761_ IATVN 766_ ITLLD 771_ INDNH 776_ PTWKD 781_ APYYI 786_ NLVEM 791_ TPPDS 796_ DVTTV 801_ VAVDP 806_ DLGEN 811_ GTLVY 816_ SIQPP 821_ NKFYS 826_ LNSTT 831_ GKIRT 836_ THAML 841_ DRENP 846_ DPHEA 851_ ELMRK 856_ IVVSV 861_ TDCGR 866_ PPLKA 871_ TSSAT 876_ VFVNL 881_ LDLND 886_ NDPTF 891_ QNLPF 896_ VAEVL 901_ EGIPA 906_ GVSIY 911_ QVVAI 916_ DLDEG 921_ LNGLV 926_ SYRMP 931_ VGMPR 936_ MDFLI 941_ NSSSG 946_ VVVTT 951_ TELDR 956_ ERIAE 961_ YQLRV 966_ VASDA 971_ GTPTK 976_ SSTST 981_ LTIHV 986_ LDVND 991_ ETPTF 996_ FPAVY 1001_ NVSVS 1006_ EDVPR 1011_ EFRVV 1016_ WLNCT 1021_ DNDVG 1026_ LNAEL 1031_ SYFIT 1036_ GGNVD 1041_ GKFSV 1046_ GYRDA 1051_ VVRTV 1056_ VGLDR 1061_ ETTAA 1066_ YMLIL 1071_ EAIDN 1076_ GPVGK 1081_ RHTGT 1086_ ATVFV 1091_ TVLDV 1096_ NDNRP 1101_ IFLQS 1106_ SYEAS 1111_ VPEDI 1116_ PEGHS 1121_ ILQLK 1126_ ATDAD 1131_ EGEFG 1136_ RVWYR 1141_ ILHGN 1146_ HGNNF 1151_ RIHVS 1156_ NGLLM 1161_ RGPRP 1166_ LDRER 1171_ NSSHV 1176_ LIVEA 1181_ YNHDL 1186_ GPMRS 1191_ SVRVI 1196_ VYVED 1201_ INDEA 1206_ PVFTQ 1211_ QQYSR 1216_ LGLRE 1221_ TAGIG 1226_ TSVIV 1231_ VQATD 1236_ RDSGD 1241_ GGLVN 1246_ YRILS 1251_ GAEGK 1256_ FEIDE 1261_ STGLI 1266_ ITVNY 1271_ LDYET 1276_ KTSYM 1281_ MNVSA 1286_ TDQAP 1291_ PFNQG 1296_ FCSVY 1301_ ITLLN 1306_ ELDEA 1311_ VQFSN 1316_ ASYEA 1321_ AILEN 1326_ LALGT 1331_ EIVRV 1336_ QAYSI 1341_ DNLNQ 1346_ ITYRF 1351_ NAYTS 1356_ TQAKA 1361_ LFKID 1366_ AITGV 1371_ ITVQG 1376_ LVDRE 1381_ KGDFY 1386_ TLTVV 1391_ ADDGG 1396_ PKVDS 1401_ TVKVY 1406_ ITVLD 1411_ ENDNS 1416_ PRFDF 1421_ TSDSA 1426_ VSIPE 1431_ DCPVG 1436_ QRVAT 1441_ VKAWD 1446_ PDAGS 1451_ NGQVV 1456_ FSLAS 1461_ GNIAG 1466_ AFEIV 1471_ TTNDS 1476_ IGEVF 1481_ VARPL 1486_ DREEL 1491_ DHYIL 1496_ QVVAS 1501_ DRGTP 1506_ PRKKD 1511_ HILQV 1516_ TILDI 1521_ NDNPP 1526_ VIESP 1531_ FGYNV 1536_ SVNEN 1541_ VGGGT 1546_ AVVQV 1551_ RATDR 1556_ DIGIN 1561_ SVLSY 1566_ YITEG 1571_ NKDMA 1576_ FRMDR 1581_ ISGEI 1586_ ATRPA 1591_ PPDRE 1596_ RQSFY 1601_ HLVAT 1606_ VEDEG 1611_ TPTLS 1616_ ATTHV 1621_ YVTIV 1626_ DENDN 1631_ APMFQ 1636_ QPHYE 1641_ VLLDE 1646_ GPDTL 1651_ NTSLI 1656_ TIQAL 1661_ DLDEG 1666_ PNGTV 1671_ TYAIV 1676_ AGNIV 1681_ NTFRI 1686_ DRHMG 1691_ VITAA 1696_ KELDY 1701_ EISHG 1706_ RYTLI 1711_ VTATD 1716_ QCPIL 1721_ SHRLT 1726_ STTTV 1731_ LVNVN 1736_ DINDN 1741_ VPTFP 1746_ RDYEG 1751_ PFEVT 1756_ EGQPG 1761_ PRVWT 1766_ FLAHD 1771_ RDSGP 1776_ NGQVE 1781_ YSIMD 1786_ GDPLG 1791_ EFVIS 1796_ PVEGV 1801_ LRVRK 1806_ DVELD 1811_ RETIA 1816_ FYNLT 1821_ ICARD 1826_ RGMPP 1831_ LSSTM 1836_ LVGIR 1841_ VLDIN 1846_ DNDPV 1851_ LLNLP 1856_ MNITI 1861_ SENSP 1866_ VSSFV 1871_ AHVLA 1876_ SDADS 1881_ GCNAR 1886_ LTFNI 1891_ TAGNR 1896_ ERAFF 1901_ INATT 1906_ GIVTV 1911_ NRPLD 1916_ RERIP 1921_ EYKLT 1926_ ISVKD 1931_ NPENP 1936_ RIARR 1941_ DYDLL 1946_ LIFLS 1951_ DENDN 1956_ HPLFT 1961_ KSTYQ 1966_ AEVME 1971_ NSPAG 1976_ TPLTV 1981_ LNGPI 1986_ LALDA 1991_ DQDIY 1996_ AVVTY 2001_ QLLGA 2006_ QSGLF 2011_ DINSS 2016_ TGVVT 2021_ VRSGV 2026_ IIDRE 2031_ AFSPP 2036_ ILELL 2041_ LLAED 2046_ IGLLN 2051_ STAHL 2056_ LITIL 2061_ DDNDN 2066_ RPTFS 2071_ PATLT 2076_ VHLLE 2081_ NCPPG 2086_ FSVLQ 2091_ VTATD 2096_ EDSGL 2101_ NGELV 2106_ YRIEA 2111_ GAQDR 2116_ FLIHL 2121_ VTGVI 2126_ RVGNA 2131_ TIDRE 2136_ EQESY 2141_ RLTVV 2146_ ATDRG 2151_ TVPLS 2156_ GTAIV 2161_ TILID 2166_ DINDS 2171_ RPEFL 2176_ NPIQT 2181_ VSVLE 2186_ SAEPG 2191_ TVIAN 2196_ ITAID 2201_ HDLNP 2206_ KLEYH 2211_ IVGIV 2216_ AKDDT 2221_ DRLVP 2226_ NQEDA 2231_ FAVNI 2236_ NTGSV 2241_ MVKSP 2246_ MNREL 2251_ VATYE 2256_ VTLSV 2261_ IDNAS 2266_ DLPER 2271_ SVSVP 2276_ NAKLT 2281_ VNVLD 2286_ VNDNT 2291_ PQFKP 2296_ FGITY 2301_ YMERI 2306_ LEGAT 2311_ PGTTL 2316_ IAVAA 2321_ VDPDK 2326_ GLNGL 2331_ VTYTL 2336_ LDLVP 2341_ PGYVQ 2346_ LEDSS 2351_ AGKVI 2356_ ANRTV 2361_ DYEEV 2366_ HWLNF 2371_ TVRAS 2376_ DNGSP 2381_ PRAAE 2386_ IPVYL 2391_ EIVDI 2396_ NDNNP 2401_ IFDQP 2406_ SYQEA 2411_ VFEDV 2416_ PVGTI 2421_ ILTVT 2426_ ATDAD 2431_ SGNFA 2436_ LIEYS 2441_ LGDGE 2446_ SKFAI 2451_ NPTTG 2456_ DIYVL 2461_ SSLDR 2466_ EKKDH 2471_ YILTA 2476_ LAKDN 2481_ PGDVA 2486_ SNRRE 2491_ NSVQV 2496_ VIQVL 2501_ DVNDC 2506_ RPQFS 2511_ KPQFS 2516_ TSVYE 2521_ NEPAG 2526_ TSVIT 2531_ MMATD 2536_ QDEGP 2541_ NGELT 2546_ YSLEG 2551_ PGVEA 2556_ FHVDM 2561_ DSGLV 2566_ TTQRP 2571_ LQSYE 2576_ KFSLT 2581_ VVATD 2586_ GGEPP 2591_ LWGTT 2596_ MLLVE 2601_ VIDVN 2606_ DNRPV 2611_ FVRPP 2616_ NGTIL 2621_ HIREE 2626_ IPLRS 2631_ NVYEV 2636_ YATDK 2641_ DEGLN 2646_ GAVRY 2651_ SFLKT 2656_ AGNRD 2661_ WEFFI 2666_ IDPIS 2671_ GLIQT 2676_ AQRLD 2681_ RESQA 2686_ VYSLI 2691_ LVASD 2696_ LGQPV 2701_ PYETM 2706_ QPLQV 2711_ ALEDI 2716_ DDNEP 2721_ LFVRP 2726_ PKGSP 2731_ QYQLL 2736_ TVPEH 2741_ SPRGT 2746_ LVGNV 2751_ TGAVD 2756_ ADEGP 2761_ NAIVY 2766_ YFIAA 2771_ GNEEK 2776_ NFHLQ 2781_ PDGCL 2786_ LVLRD 2791_ LDRER 2796_ EAIFS 2801_ FIVKA 2806_ SSNRS 2811_ WTPPR 2816_ GPSPT 2821_ LDLVA 2826_ DLTLQ 2831_ EVRVV 2836_ LEDIN 2841_ DQPPR 2846_ FTKAE 2851_ YTAGV 2856_ ATDAK 2861_ VGSEL 2866_ IQVLA 2871_ LDADI 2876_ GNNSL 2881_ VFYSI 2886_ LAIHY 2891_ FRALA 2896_ NDSED 2901_ VGQVF 2906_ TMGSM 2911_ DGILR 2916_ TFDLF 2921_ MAYSP 2926_ GYFVV 2931_ DIVAR 2936_ DLAGH 2941_ NDTAI 2946_ IGIYI 2951_ LRDDQ 2956_ RVKIV 2961_ INEIP 2966_ DRVRG 2971_ FEEEF 2976_ IHLLS 2981_ NITGA 2986_ IVNTD 2991_ NVQFH 2996_ VDKKG 3001_ RVNFA 3006_ QTELL 3011_ IHVVN 3016_ RDTNR 3021_ ILDVD 3026_ RVIQM 3031_ IDENK 3036_ EQLRN 3041_ LFRNY 3046_ NVLDV 3051_ QPAIS 3056_ VRLPD 3061_ DMSAL 3066_ QMAII 3071_ VLAIL 3076_ LFLAA 3081_ MLFVL 3086_ MNWYY 3091_ RTVHK 3096_ RKLKA 3101_ IVAGS 3106_ AGNRG 3111_ FIDIM 3116_ DMPNT 3121_ NKYSF 3126_ DGANP 3131_ VWLDP 3136_ FCRNL 3141_ ELAAQ 3146_ AEHED 3151_ DLPEN 3156_ LSEIA 3161_ DLWNS 3166_ PTRTH 3171_ GTFGR 3176_ EPAAV 3181_ KPDDD 3186_ RYLRA 3191_ AIQEY 3196_ DNIAK 3201_ LGQII 3206_ REGPI 3211_ KGSLL 3216_ KVVLE 3221_ DYLRL 3226_ KKLFA 3231_ QRMVQ 3236_ KASSC 3241_ HSSIS 3246_ ELIQT 3251_ ELDEE 3256_ PGDHS 3261_ PGQGS 3266_ LRFRH 3271_ KPPVE 3276_ LKGPD 3281_ GIHVV 3286_ HGSTG 3291_ TLLAT 3296_ DLNSL 3301_ PEEDQ 3306_ KGLGR 3311_ SLETL 3316_ TAAEA 3321_ TAFER 3326_ NARTE 3331_ SAKST 3336_ PLHKL 3341_ RDVIM 3346_ETPLE
1: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing