Gene name: CXCL16

Uniprot entry:

Q9H2A7

Protein names:

C-X-C motif chemokine 16 (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein) (SR-PSOX) (Small-inducible cytokine B16) (Transmembrane chemokine CXCL16)

Protein sequence:

1_MGRDL 6_ RPGSR 11_ VLLLL 16_ LLLLL 21_ VYLTQ 26_ PGNGN 31_ EGSVT 36_ GSCYC 41_ GKRIS 46_ SDSPP 51_ SVQFM 56_ NRLRK 61_ HLRAY 66_ HRCLY 71_ YTRFQ 76_ LLSWS 81_ VCGGN 86_ KDPWV 91_ QELMS 96_ CLDLK 101_ ECGHA 106_ YSGIV 111_ AHQKH 116_ LLPTS 121_ PPISQ 126_ ASEGA 131_ SSDIH 136_ TPAQM 141_ LLSTL 146_ QSTQR 151_ PTLPV 156_ GSLSS 161_ DKELT 166_ RPNET 171_ TIHTA 176_ GHSLA 181_ AGPEA 186_ GENQK 191_ QPEKN 196_ AGPTA 201_ RTSAT 206_ VPVLC 211_ LLAII 216_ FILTA 221_ ALSYV 226_ LCKRR 231_ RGQSP 236_ QSSPD 241_ LPVHY 246_IPVAP

Protein annotations

Protein functions:

1: Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo