Protein tweety homolog 1 (hTTY1)
1_MGAPP 6_ GYRPS 11_ AWVHL 16_ LHQLP 21_ RADFQ 26_ LRPVP 31_ SVFAP 36_ QEQEY 41_ QQALL 46_ LVAAL 51_ AGLGL 56_ GLSLI 61_ FIAVY 66_ LIRFC 71_ CCRPP 76_ EPPGS 81_ KIPSP 86_ GGGCV 91_ TWSCI 96_ VALLA 101_ GCTGI 106_ GIGFY 111_ GNSET 116_ SDGVS 121_ QLSSA 126_ LLHAN 131_ HTLST 136_ IDHLV 141_ LETVE 146_ RLGEA 151_ VRTEL 156_ TTLEE 161_ VLEPR 166_ TELVA 171_ AARGA 176_ RRQAE 181_ AAAQQ 186_ LQGLA 191_ FWQGV 196_ PLSPL 201_ QVAEN 206_ VSFVE 211_ EYRWL 216_ AYVLL 221_ LLLEL 226_ LVCLF 231_ TLLGL 236_ AKQSK 241_ WLVIV 246_ MTVMS 251_ LLVLV 256_ LSWGS 261_ MGLEA 266_ ATAVG 271_ LSDFC 276_ SNPDP 281_ YVLNL 286_ TQEET 291_ GLSSD 296_ ILSYY 301_ LLCNR 306_ AVSNP 311_ FQQRL 316_ TLSQR 321_ ALANI 326_ HSQLL 331_ GLERE 336_ AVPQF 341_ PSAQK 346_ PLLSL 351_ EETLN 356_ VTEGN 361_ FHQLV 366_ ALLHC 371_ RSLHK 376_ DYGAA 381_ LRGLC 386_ EDALE 391_ GLLFL 396_ LLFSL 401_ LSAGA 406_ LATAL 411_ CSLPR 416_ AWALF 421_ PPSDD 426_ YDDTD 431_ DDDPF 436_ NPQES 441_KRFVQ
1: Calcium-independent, swelling-dependent volume-regulated anion channel (VRAC-swell) which plays a pivotal role in the process of regulatory volume decrease (RVD) in the brain through the efflux of anions like chloride and organic osmolytes like glutamate
2: Ca(2+)-independent, swelling-activated chloride channel, possibly involved in regulation of cell volume