Gene name: CDC42EP4

Uniprot entry:

Q9H3Q1

Protein names:

Cdc42 effector protein 4 (Binder of Rho GTPases 4)

Protein sequence:

1_MPILK 6_ QLVSS 11_ SVHSK 16_ RRSRA 21_ DLTAE 26_ MISAP 31_ LGDFR 36_ HTMHV 41_ GRAGD 46_ AFGDT 51_ SFLNS 56_ KAGEP 61_ DGESL 66_ DEQPS 71_ SSSSK 76_ RSLLS 81_ RKFRG 86_ SKRSQ 91_ SVTRG 96_ EREQR 101_ DMLGS 106_ LRDSA 111_ LFVKN 116_ AMSLP 121_ QLNEK 126_ EAAEK 131_ GTSKL 136_ PKSLS 141_ SSPVK 146_ KANDG 151_ EGGDE 156_ EAGTE 161_ EAVPR 166_ RNGAA 171_ GPHSP 176_ DPLLD 181_ EQAFG 186_ DLTDL 191_ PVVPK 196_ ATYGL 201_ KHAES 206_ IMSFH 211_ IDLGP 216_ SMLGD 221_ VLSIM 226_ DKEEW 231_ DPEEG 236_ EGGYH 241_ GDEGA 246_ AGTIT 251_ QAPPY 256_ AVAAP 261_ PLARQ 266_ EGKAG 271_ PDLPS 276_ LPSHA 281_ LEDEG 286_ WAAAA 291_ PSPGS 296_ ARSMG 301_ SHTTR 306_ DSSSL 311_ SSCTS 316_ GILEE 321_ RSPAF 326_ RGPDR 331_ ARAAV 336_ SRQPD 341_ KEFSF 346_ MDEEE 351_EDEIR

Protein annotations

Protein functions:

1: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts