Centromere protein H (CENP-H) (Interphase centromere complex protein 35)
1_MEEQP 6_ QMQDA 11_ DEPAD 16_ SGGEG 21_ RAGGP 26_ PQVAG 31_ AQAAC 36_ SEDRM 41_ TLLLR 46_ LRAQT 51_ KQQLL 56_ EYKSM 61_ VDASE 66_ EKTPE 71_ QIMQE 76_ KQIEA 81_ KIEDL 86_ ENEIE 91_ EVKVA 96_ FEIKK 101_ LALDR 106_ MRLST 111_ ALKKN 116_ LEKIS 121_ RQSSV 126_ LMDNM 131_ KHLLE 136_ LNKLI 141_ MKSQQ 146_ ESWDL 151_ EEKLL 156_ DIRKK 161_ RLQLK 166_ QASES 171_ KLLEI 176_ QTEKN 181_ KQKID 186_ LDSME 191_ NSERI 196_ KIIRQ 201_ NLQME 206_ IKITT 211_ VIQHV 216_ FQNLI 221_ LGSKV 226_ NWAED 231_ PALKE 236_ IVLQL 241_EKNVD
1: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate