GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M)
1_MGSTK 6_ HWGEW 11_ LLNLK 16_ VAPAG 21_ VFGVA 26_ FLARV 31_ ALVFY 36_ GVFQD 41_ RTLHV 46_ RYTDI 51_ DYQVF 56_ TDAAR 61_ FVTEG 66_ RSPYL 71_ RATYR 76_ YTPLL 81_ GWLLT 86_ PNIYL 91_ SELFG 96_ KFLFI 101_ SCDLL 106_ TAFLL 111_ YRLLL 116_ LKGLG 121_ RRQAC 126_ GYCVF 131_ WLLNP 136_ LPMAV 141_ SSRGN 146_ ADSIV 151_ ASLVL 156_ MVLYL 161_ IKKRL 166_ VACAA 171_ VFYGF 176_ AVHMK 181_ IYPVT 186_ YILPI 191_ TLHLL 196_ PDRDN 201_ DKSLR 206_ QFRYT 211_ FQACL 216_ YELLK 221_ RLCNR 226_ AVLLF 231_ VAVAG 236_ LTFFA 241_ LSFGF 246_ YYEYG 251_ WEFLE 256_ HTYFY 261_ HLTRR 266_ DIRHN 271_ FSPYF 276_ YMLYL 281_ TAESK 286_ WSFSL 291_ GIAAF 296_ LPQLI 301_ LLSAV 306_ SFAYY 311_ RDLVF 316_ CCFLH 321_ TSIFV 326_ TFNKV 331_ CTSQY 336_ FLWYL 341_ CLLPL 346_ VMPLV 351_ RMPWK 356_ RAVVL 361_ LMLWF 366_ IGQAM 371_ WLAPA 376_ YVLEF 381_ QGKNT 386_ FLFIW 391_ LAGLF 396_ FLLIN 401_ CSILI 406_ QIISH 411_ YKEEP 416_LTERI
1: Catalytic subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis