Major facilitator superfamily domain-containing protein 1 (Smooth muscle cell-associated protein 4) (SMAP-4)
1_MEEED 6_ EEARA 11_ LLAGG 16_ PDEAD 21_ RGAPA 26_ APGAL 31_ PALCD 36_ PSRLA 41_ HRLLV 46_ LLLMC 51_ FLGFG 56_ SYFCY 61_ DNPAA 66_ LQTQV 71_ KRDMQ 76_ VNTTK 81_ FMLLY 86_ AWYSW 91_ PNVVL 96_ CFFGG 101_ FLIDR 106_ VFGIR 111_ WGTII 116_ FSCFV 121_ CIGQV 126_ VFALG 131_ GIFNA 136_ FWLME 141_ FGRFV 146_ FGIGG 151_ ESLAV 156_ AQNTY 161_ AVSWF 166_ KGKEL 171_ NLVFG 176_ LQLSM 181_ ARIGS 186_ TVNMN 191_ LMGWL 196_ YSKIE 201_ ALLGS 206_ AGHTT 211_ LGITL 216_ MIGGI 221_ TCILS 226_ LICAL 231_ ALAYL 236_ DQRAE 241_ RILHK 246_ EQGKT 251_ GEVIK 256_ LTDVK 261_ DFSLP 266_ LWLIF 271_ IICVC 276_ YYVAV 281_ FPFIG 286_ LGKVF 291_ FTEKF 296_ GFSSQ 301_ AASAI 306_ NSVVY 311_ VISAP 316_ MSPVF 321_ GLLVD 326_ KTGKN 331_ IIWVL 336_ CAVAA 341_ TLVSH 346_ MMLAF 351_ TMWNP 356_ WIAMC 361_ LLGLS 366_ YSLLA 371_ CALWP 376_ MVAFV 381_ VPEHQ 386_ LGTAY 391_ GFMQS 396_ IQNLG 401_ LAIIS 406_ IIAGM 411_ ILDSR 416_ GYLFL 421_ EVFFI 426_ ACVSL 431_ SLLSV 436_ VLLYL 441_ VNRAQ 446_ GGNLN 451_ YSARQ 456_REEIK
1: Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol (PubMed:38507452). Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion (PubMed:30910009). Also essential for liver homeostasis (By similarity)