Tyrosine-protein kinase Srms (EC 2.7.10.2)
1_MEPFL 6_ RRRLA 11_ FLSFF 16_ WDKIW 21_ PAGGE 26_ PDHGT 31_ PGSLD 36_ PNTDP 41_ VPTLP 46_ AEPCS 51_ PFPQL 56_ FLALY 61_ DFTAR 66_ CGGEL 71_ SVRRG 76_ DRLCA 81_ LEEGG 86_ GYIFA 91_ RRLSG 96_ QPSAG 101_ LVPIT 106_ HVAKA 111_ SPETL 116_ SDQPW 121_ YFSGV 126_ SRTQA 131_ QQLLL 136_ SPPNE 141_ PGAFL 146_ IRPSE 151_ SSLGG 156_ YSLSV 161_ RAQAK 166_ VCHYR 171_ VSMAA 176_ DGSLY 181_ LQKGR 186_ LFPGL 191_ EELLT 196_ YYKAN 201_ WKLIQ 206_ NPLLQ 211_ PCMPQ 216_ KAPRQ 221_ DVWER 226_ PHSEF 231_ ALGRK 236_ LGEGY 241_ FGEVW 246_ EGLWL 251_ GSLPV 256_ AIKVI 261_ KSANM 266_ KLTDL 271_ AKEIQ 276_ TLKGL 281_ RHERL 286_ IRLHA 291_ VCSGG 296_ EPVYI 301_ VTELM 306_ RKGNL 311_ QAFLG 316_ TPEGR 321_ ALRLP 326_ PLLGF 331_ ACQVA 336_ EGMSY 341_ LEEQR 346_ VVHRD 351_ LAARN 356_ VLVDD 361_ GLACK 366_ VADFG 371_ LARLL 376_ KDDIY 381_ SPSSS 386_ SKIPV 391_ KWTAP 396_ EAANY 401_ RVFSQ 406_ KSDVW 411_ SFGVL 416_ LHEVF 421_ TYGQC 426_ PYEGM 431_ TNHET 436_ LQQIM 441_ RGYRL 446_ PRPAA 451_ CPAEV 456_ YVLML 461_ ECWRS 466_ SPEER 471_ PSFAT 476_ LREKL 481_HAIHR
1: Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues (PubMed:23822091). Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues (PubMed:29496907). Phosphorylation of KHDRBS1 is EGF-dependent (PubMed:29496907). Phosphorylates OTUB1, promoting deubiquitination of RPTOR (PubMed:35927303)