Protein ABHD16B (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 16B) (Abhydrolase domain-containing protein 16B)
1_MCVIC 6_ FVKAL 11_ VRVFK 16_ IYLTA 21_ SYTYP 26_ FRGWP 31_ VAFRW 36_ DDVRA 41_ VGRSS 46_ SHRAL 51_ TCAAA 56_ AAGVW 61_ LLRDE 66_ TLGGD 71_ ALGRP 76_ PRGAR 81_ SQAQC 86_ LLQQL 91_ RELPG 96_ QLASY 101_ ALAHS 106_ LGRWL 111_ VYPGS 116_ VSLMT 121_ RALLP 126_ LLQQG 131_ QERLV 136_ ERYHG 141_ RRAKL 146_ VACDG 151_ NEIDT 156_ MFMDR 161_ RQHPG 166_ SHVHG 171_ PRLVI 176_ CCEGN 181_ AGFYE 186_ MGCLS 191_ APLEA 196_ GYSVL 201_ GWNHP 206_ GFGSS 211_ TGVPF 216_ PQHDA 221_ NAMDV 226_ VVEYA 231_ LHRLH 236_ FPPAH 241_ LVVYG 246_ WSVGG 251_ FTATW 256_ ATMTY 261_ PELGA 266_ LVLDA 271_ TFDDL 276_ VPLAL 281_ KVMPH 286_ SWKGL 291_ VVRTV 296_ REHFN 301_ LNVAE 306_ QLCCY 311_ PGPVL 316_ LLRRT 321_ QDDVV 326_ STSGR 331_ LRPLS 336_ PGDVE 341_ GNRGN 346_ ELLLR 351_ LLEHR 356_ YPVVM 361_ AREGR 366_ AVVTR 371_ WLRAG 376_ SLAQE 381_ AAFYA 386_ RYRVD 391_ EDWCL 396_ ALLRS 401_ YRARC 406_ EEELE 411_ GEEAL 416_ GPHGP 421_ AFPWL 426_ VGQGL 431_ SSRRR 436_ RRLAL 441_ FLARK 446_ HLKNV 451_ EATHF 456_ SPLEP 461_EEFQL
1: Hydrolyzes the sn-1 position of glycerophospholipids with high specificity towards phosphatidylserine (PS), PS-PLA1 enzyme (PubMed:36841071). Also hydrolyzes the acyl chain of glycerolipids with a preference for the monoacylglycerol (MAG) 1-acylglycerol, MAG lipase (PubMed:36841071). Plays a regulatory role in cellular lipid homeostasis by modulating genes involved in neutral lipid degradation and in phospholipid synthesis and composition (PubMed:37944658)