Gene name: GOLPH3

Uniprot entry:

Q9H4A6

Protein names:

Golgi phosphoprotein 3 (Coat protein GPP34) (Mitochondrial DNA absence factor) (MIDAS)

Protein sequence:

1_MTSLT 6_ QRSSG 11_ LVQRR 16_ TEASR 21_ NAADK 26_ ERAAG 31_ GGAGS 36_ SEDDA 41_ QSRRD 46_ EQDDD 51_ DKGDS 56_ KETRL 61_ TLMEE 66_ VLLLG 71_ LKDRE 76_ GYTSF 81_ WNDCI 86_ SSGLR 91_ GCMLI 96_ ELALR 101_ GRLQL 106_ EACGM 111_ RRKSL 116_ LTRKV 121_ ICKSD 126_ APTGD 131_ VLLDE 136_ ALKHV 141_ KETQP 146_ PETVQ 151_ NWIEL 156_ LSGET 161_ WNPLK 166_ LHYQL 171_ RNVRE 176_ RLAKN 181_ LVEKG 186_ VLTTE 191_ KQNFL 196_ LFDMT 201_ THPLT 206_ NNNIK 211_ QRLIK 216_ KVQEA 221_ VLDKW 226_ VNDPH 231_ RMDRR 236_ LLALI 241_ YLAHA 246_ SDVLE 251_ NAFAP 256_ LLDEQ 261_ YDLAT 266_ KRVRQ 271_ LLDLD 276_ PEVEC 281_ LKANT 286_ NEVLW 291_AVVAA

Protein annotations

Protein functions:

1: Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Has also been involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part. May play an indirect role in cell migration. Has also been involved in the modulation of mTOR signaling. May also be involved in the regulation of mitochondrial lipids biosynthesis