tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 3)
1_MLTQL 6_ KAKSE 11_ GKLAK 16_ QICKV 21_ VLDHF 26_ EKQYS 31_ KELGD 36_ AWNTV 41_ REILT 46_ SPSCW 51_ QYAVL 56_ LNRFN 61_ YPFEL 66_ EKDLH 71_ LKGYH 76_ TLSQG 81_ SLPNY 86_ PKSVK 91_ CYLSR 96_ TPGRI 101_ PSERH 106_ QIGNL 111_ KKYYL 116_ LNAAS 121_ LLPVL 126_ ALELR 131_ DGEKV 136_ LDLCA 141_ APGGK 146_ SIALL 151_ QCACP 156_ GYLHC 161_ NEYDS 166_ LRLRW 171_ LRQTL 176_ ESFIP 181_ QPLIN 186_ VIKVS 191_ ELDGR 196_ KMGDA 201_ QPEMF 206_ DKVLV 211_ DAPCS 216_ NDRSW 221_ LFSSD 226_ SQKAS 231_ CRISQ 236_ RRNLP 241_ LLQIE 246_ LLRSA 251_ IKALR 256_ PGGIL 261_ VYSTC 266_ TLSKA 271_ ENQDV 276_ ISEIL 281_ NSHGN 286_ IMPMD 291_ IKGIA 296_ RTCSH 301_ DFTFA 306_ PTGQE 311_ CGLLV 316_ IPDKG 321_ KAWGP 326_ MYVAK 331_LKKSW
1: Mitochondrial tRNA methyltransferase that mediates methylation of cytosine to 5-methylcytosine (m5C) at position 34 of mt-tRNA(Met) (PubMed:27214402, PubMed:27356879, PubMed:27497299). mt-tRNA(Met) methylation at cytosine(34) takes place at the wobble position of the anticodon and initiates the formation of 5-formylcytosine (f(5)c) at this position (PubMed:27214402, PubMed:27356879, PubMed:27497299). mt-tRNA(Met) containing the f(5)c modification at the wobble position enables recognition of the AUA codon in addition to the AUG codon, expanding codon recognition in mitochondrial translation (PubMed:27356879, PubMed:27497299)