Gene name: DENND2D

Uniprot entry:

Q9H6A0

Protein names:

DENN domain-containing protein 2D

Protein sequence:

1_MEGQV 6_ VGRVF 11_ RLFQR 16_ RLLQL 21_ RAGPP 26_ QDNSG 31_ EALKE 36_ PERAQ 41_ EHSLP 46_ NFAGG 51_ QHFFE 56_ YLLVV 61_ SLKKK 66_ RSEDD 71_ YEPII 76_ TYQFP 81_ KRENL 86_ LRGQQ 91_ EEEER 96_ LLKAI 101_ PLFCF 106_ PDGNE 111_ WASLT 116_ EYPRE 121_ TFSFV 126_ LTNVD 131_ GSRKI 136_ GYCRR 141_ LLPAG 146_ PGPRL 151_ PKVYC 156_ IISCI 161_ GCFGL 166_ FSKIL 171_ DEVEK 176_ RHQIS 181_ MAVIY 186_ PFMQG 191_ LREAA 196_ FPAPG 201_ KTVTL 206_ KSFIP 211_ DSGTE 216_ FISLT 221_ RPLDS 226_ HLEHV 231_ DFSSL 236_ LHCLS 241_ FEQIL 246_ QIFAS 251_ AVLER 256_ KIIFL 261_ AEGLS 266_ TLSQC 271_ IHAAA 276_ ALLYP 281_ FSWAH 286_ TYIPV 291_ VPESL 296_ LATVC 301_ CPTPF 306_ MVGVQ 311_ MRFQQ 316_ EVMDS 321_ PMEEV 326_ LLVNL 331_ CEGTF 336_ LMSVG 341_ DEKDI 346_ LPPKL 351_ QDDIL 356_ DSLGQ 361_ GINEL 366_ KTAEQ 371_ INEHV 376_ SGPFV 381_ QFFVK 386_ IVGHY 391_ ASYIK 396_ REANG 401_ QGHFQ 406_ ERSFC 411_ KALTS 416_ KTNRR 421_ FVKKF 426_ VKTQL 431_ FSLFI 436_ QEAEK 441_ SKNPP 446_ AGYFQ 451_ QKILE 456_ YEEQK 461_ KQKKP 466_REKTV

Protein annotations

Protein functions:

1: Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form