5-azacytidine-induced protein 2 (NF-kappa-B-activating kinase-associated protein 1) (Nak-associated protein 1) (Nap1) (TILP)
1_MDALV 6_ EDDIC 11_ ILNHE 16_ KAHKR 21_ DTVTP 26_ VSIYS 31_ GDESV 36_ ASHFA 41_ LVTAY 46_ EDIKK 51_ RLKDS 56_ EKENS 61_ LLKKR 66_ IRFLE 71_ EKLIA 76_ RFEEE 81_ TSSVG 86_ REQVN 91_ KAYHA 96_ YREVC 101_ IDRDN 106_ LKSKL 111_ DKMNK 116_ DNSES 121_ LKVLN 126_ EQLQS 131_ KEVEL 136_ LQLRT 141_ EVETQ 146_ QVMRN 151_ LNPPS 156_ SNWEV 161_ EKLSC 166_ DLKIH 171_ GLEQE 176_ LELMR 181_ KECSD 186_ LKIEL 191_ QKAKQ 196_ TDPYQ 201_ EDNLK 206_ SRDLQ 211_ KLSIS 216_ SDNMQ 221_ HAYWE 226_ LKREM 231_ SNLHL 236_ VTQVQ 241_ AELLR 246_ KLKTS 251_ TAIKK 256_ ACAPV 261_ GCSED 266_ LGRDS 271_ TKLHL 276_ MNFTA 281_ TYTRH 286_ PPLLP 291_ NGKAL 296_ CHTTS 301_ SPLPG 306_ DVKVL 311_ SEKAI 316_ LQSWT 321_ DNERS 326_ IPNDG 331_ TCFQE 336_ HSSYG 341_ RNSLE 346_ DNSWV 351_ FPSPP 356_ KSSET 361_ AFGET 366_ KTKTL 371_ PLPNL 376_ PPLHY 381_ LDQHN 386_QNCLY
1: Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity (PubMed:14560022, PubMed:21931631). Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization (PubMed:14560022, PubMed:21931631). Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1 (PubMed:14560022, PubMed:21931631). Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B (PubMed:14560022, PubMed:21931631). Participates in IFNB promoter activation via TICAM1 (PubMed:15611223)