Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.259) (EC 2.4.1.261) (Asparagine-linked glycosylation protein 9 homolog) (Disrupted in bipolar disorder protein 1) (Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase) (Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase)
1_MASRG 6_ ARQRL 11_ KGSGA 16_ SSGDT 21_ APAAD 26_ KLREL 31_ LGSRE 36_ AGGAE 41_ HRTEL 46_ SGNKA 51_ GQVWA 56_ PEGST 61_ AFKCL 66_ LSARL 71_ CAALL 76_ SNISD 81_ CDETF 86_ NYWEP 91_ THYLI 96_ YGEGF 101_ QTWEY 106_ SPAYA 111_ IRSYA 116_ YLLLH 121_ AWPAA 126_ FHARI 131_ LQTNK 136_ ILVFY 141_ FLRCL 146_ LAFVS 151_ CICEL 156_ YFYKA 161_ VCKKF 166_ GLHVS 171_ RMMLA 176_ FLVLS 181_ TGMFC 186_ SSSAF 191_ LPSSF 196_ CMYTT 201_ LIAMT 206_ GWYMD 211_ KTSIA 216_ VLGVA 221_ AGAIL 226_ GWPFS 231_ AALGL 236_ PIAFD 241_ LLVMK 246_ HRWKS 251_ FFHWS 256_ LMALI 261_ LFLVP 266_ VVVID 271_ SYYYG 276_ KLVIA 281_ PLNIV 286_ LYNVF 291_ TPHGP 296_ DLYGT 301_ EPWYF 306_ YLING 311_ FLNFN 316_ VAFAL 321_ ALLVL 326_ PLTSL 331_ MEYLL 336_ QRFHV 341_ QNLGH 346_ PYWLT 351_ LAPMY 356_ IWFII 361_ FFIQP 366_ HKEER 371_ FLFPV 376_ YPLIC 381_ LCGAV 386_ ALSAL 391_ QKCYH 396_ FVFQR 401_ YRLEH 406_ YTVTS 411_ NWLAL 416_ GTVFL 421_ FGLLS 426_ FSRSV 431_ ALFRG 436_ YHGPL 441_ DLYPE 446_ FYRIA 451_ TDPTI 456_ HTVPE 461_ GRPVN 466_ VCVGK 471_ EWYRF 476_ PSSFL 481_ LPDNW 486_ QLQFI 491_ PSEFR 496_ GQLPK 501_ PFAEG 506_ PLATR 511_ IVPTD 516_ MNDQN 521_ LEEPS 526_ RYIDI 531_ SKCHY 536_ LVDLD 541_ TMRET 546_ PREPK 551_ YSSNK 556_ EEWIS 561_ LAYRP 566_ FLDAS 571_ RSSKL 576_ LRAFY 581_ VPFLS 586_ DQYTV 591_ YVNYT 596_ ILKPR 601_ KAKQI 606_RKKSG
1: Mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, catalyzes the addition of the seventh and ninth alpha-1,2-linked mannose residues to Man(6)GlcNAc(2)-PP-dolichol and Man(8)GlcNAc(2)-PP-dolichol respectively