Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus)
1_MFWKL 6_ SLSLF 11_ LVAVL 16_ VKVAE 21_ ARKNR 26_ PAGAI 31_ PSPYK 36_ DGSSN 41_ NSERW 46_ QHQIK 51_ EVLAS 56_ SQEAL 61_ VVTER 66_ KYLKS 71_ DWCKT 76_ QPLRQ 81_ TVSEE 86_ GCRSR 91_ TILNR 96_ FCYGQ 101_ CNSFY 106_ IPRHV 111_ KKEEE 116_ SFQSC 121_ AFCKP 126_ QRVTS 131_ VLVEL 136_ ECPGL 141_ DPPFR 146_ LKKIQ 151_ KVKQC 156_ RCMSV 161_NLSDS
1: Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells