dCTP pyrophosphatase 1 (EC 3.6.1.12) (Deoxycytidine-triphosphatase 1) (dCTPase 1) (RS21C6) (XTP3-transactivated gene A protein)
1_MSVAG 6_ GEIRG 11_ DTGGE 16_ DTAAP 21_ GRFSF 26_ SPEPT 31_ LEDIR 36_ RLHAE 41_ FAAER 46_ DWEQF 51_ HQPRN 56_ LLLAL 61_ VGEVG 66_ ELAEL 71_ FQWKT 76_ DGEPG 81_ PQGWS 86_ PRERA 91_ ALQEE 96_ LSDVL 101_ IYLVA 106_ LAARC 111_ RVDLP 116_ LAVLS 121_ KMDIN 126_ RRRYP 131_ AHLAR 136_ SSSRK 141_ YTELP 146_ HGAIS 151_ EDQAV 156_ GPADI 161_PCDST
1: Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism