Inactive tyrosine-protein kinase PEAK1 (Pseudopodium-enriched atypical kinase 1) (Sugen kinase 269) (Tyrosine-protein kinase SgK269)
1_MSACN 6_ TFTEH 11_ VWKPG 16_ ECKNC 21_ FKPKS 26_ LHQLP 31_ PDPEK 36_ APITH 41_ GNVKT 46_ NANHS 51_ NNHRI 56_ RNTGN 61_ FRPPV 66_ AKKPT 71_ IAVKP 76_ TMIVA 81_ DGQSI 86_ CGELS 91_ IQEHC 96_ ENKPV 101_ IIGWN 106_ RNRAA 111_ LSQKP 116_ LNNNN 121_ EDDEG 126_ ISHVP 131_ KPYGN 136_ NDSAK 141_ KMSDN 146_ NNGLT 151_ EVLKE 156_ IAGLD 161_ TAPQI 166_ RGNET 171_ NSRET 176_ FLGRI 181_ NDCYK 186_ RSLER 191_ KLPPS 196_ CMIGG 201_ IKETQ 206_ GKHVI 211_ LSGST 216_ EVISN 221_ EGGRF 226_ CYPEF 231_ SSGEE 236_ SEEDV 241_ LFSNM 246_ EEEHE 251_ SWDES 256_ DEELL 261_ AMEIR 266_ MRGQP 271_ RFANF 276_ RANTL 281_ SPVRF 286_ FVDKK 291_ WNTIP 296_ LRNKS 301_ LQRIC 306_ AVDYD 311_ DSYDE 316_ ILNGY 321_ EENSV 326_ VSYGQ 331_ GSIQS 336_ MVSSD 341_ STSPD 346_ SSLTE 351_ ESRSE 356_ TASSL 361_ SQKIC 366_ NGGLS 371_ PGNPG 376_ DSKDM 381_ KEIEP 386_ NYESP 391_ SSNNQ 396_ DKDSS 401_ QASKS 406_ SIKVP 411_ ETHKA 416_ VLALR 421_ LEEKD 426_ GKIAV 431_ QTEKE 436_ ESKAS 441_ TDVAG 446_ QAVTI 451_ NLVPT 456_ EEQAK 461_ PYRVV 466_ NLEQP 471_ LCKPY 476_ TVVDV 481_ SAAMA 486_ SEHLE 491_ GPVNS 496_ PKTKS 501_ SSSTP 506_ NSPVT 511_ SSSLT 516_ PGQIS 521_ AHFQK 526_ SSAIR 531_ YQEVW 536_ TSSTS 541_ PRQKI 546_ PKVEL 551_ ITSGT 556_ GPNVP 561_ PRKNC 566_ HKSAP 571_ TSPTA 576_ TNISS 581_ KTIPV 586_ KSPNL 591_ SEIKF 596_ NSYNN 601_ AGMPP 606_ FPIII 611_ HDEPT 616_ YARSS 621_ KNAIK 626_ VPIVI 631_ NPNAY 636_ DNLAI 641_ YKSFL 646_ GTSGE 651_ LSVKE 656_ KTTSV 661_ ISHTY 666_ EEIET 671_ ESKVP 676_ DNTTS 681_ KTTDC 686_ LQTKG 691_ FSNST 696_ EHKRG 701_ SVAQK 706_ VQEFN 711_ NCLNR 716_ GQSSP 721_ QRSYS 726_ SSHSS 731_ PAKIQ 736_ RATQE 741_ PVAKI 746_ EGTQE 751_ SQMVG 756_ SSSTR 761_ EKAST 766_ VLSQI 771_ VASIQ 776_ PPQSP 781_ PETPQ 786_ SGPKA 791_ CSVEE 796_ LYAIP 801_ PDADV 806_ AKSTP 811_ KSTPV 816_ RPKSL 821_ FTSQP 826_ SGEAE 831_ APQTT 836_ DSPTT 841_ KVQKD 846_ PSIKP 851_ VTPSP 856_ SKLVT 861_ SPQSE 866_ PPAPF 871_ PPPRS 876_ TSSPY 881_ HAGNL 886_ LQRHF 891_ TNWTK 896_ PTSPT 901_ RSTEA 906_ ESVLH 911_ SEGSR 916_ RAADA 921_ KPKRW 926_ ISFKS 931_ FFRRR 936_ KTDEE 941_ DDKEK 946_ EREKG 951_ KLVGL 956_ DGTVI 961_ HMLPP 966_ PPVQR 971_ HHWFT 976_ EAKGE 981_ SSEKP 986_ AIVFM 991_ YRCDP 996_ AQGQL 1001_ SVDQS 1006_ KARTD 1011_ QAAVM 1016_ EKGRA 1021_ ENALL 1026_ QDSEK 1031_ KRSHS 1036_ SPSQI 1041_ PKKIL 1046_ SHMTH 1051_ EVTED 1056_ FSPRD 1061_ PRTVV 1066_ GKQDG 1071_ RGCTS 1076_ VTTAL 1081_ SLPEL 1086_ EREDG 1091_ KEDIS 1096_ DPMDP 1101_ NPCSA 1106_ TYSNL 1111_ GQSRA 1116_ AMIPP 1121_ KQPRQ 1126_ PKGAV 1131_ DDAIA 1136_ FGGKT 1141_ DQEAP 1146_ NASQP 1151_ TPPPL 1156_ PKKMI 1161_ IRANT 1166_ EPISK 1171_ DLQKS 1176_ MESSL 1181_ CVMAN 1186_ PTYDI 1191_ DPNWD 1196_ ASSAG 1201_ SSISY 1206_ ELKGL 1211_ DIESY 1216_ DSLER 1221_ PLRKE 1226_ RPVPS 1231_ AANSI 1236_ SSLTT 1241_ LSIKD 1246_ RFSNS 1251_ MESLS 1256_ SRRGP 1261_ SCRQG 1266_ RGIQK 1271_ PQRQA 1276_ LYRGL 1281_ ENREE 1286_ VVGKI 1291_ RSLHT 1296_ DALKK 1301_ LAVKC 1306_ EDLFM 1311_ AGQKD 1316_ QLRFG 1321_ VDSWS 1326_ DFRLT 1331_ SDKPC 1336_ CEAGD 1341_ AVYYT 1346_ ASYAK 1351_ DPLNN 1356_ YAVKI 1361_ CKSKA 1366_ KESQQ 1371_ YYHSL 1376_ AVRQS 1381_ LAVHF 1386_ NIQQD 1391_ CGHFL 1396_ AEVPN 1401_ RLLPW 1406_ EDPDD 1411_ PEKDE 1416_ DDMEE 1421_ TEEDA 1426_ KGETD 1431_ GKNPK 1436_ PCSEA 1441_ ASSQK 1446_ ENQGV 1451_ MSKKQ 1456_ RSHVV 1461_ VITRE 1466_ VPCLT 1471_ VADFV 1476_ RDSLA 1481_ QHGKS 1486_ PDLYE 1491_ RQVCL 1496_ LLLQL 1501_ CSGLE 1506_ HLKPY 1511_ HVTHC 1516_ DLRLE 1521_ NLLLV 1526_ HYQPG 1531_ GTAQG 1536_ FGPAE 1541_ PSPTS 1546_ SYPTR 1551_ LIVSN 1556_ FSQAK 1561_ QKSHL 1566_ VDPEI 1571_ LRDQS 1576_ RLAPE 1581_ IITAT 1586_ QYKKC 1591_ DEFQT 1596_ GILIY 1601_ EMLHL 1606_ PNPFD 1611_ ENPEL 1616_ KEREY 1621_ TRADL 1626_ PRIPF 1631_ RSPYS 1636_ RGLQQ 1641_ LASCL 1646_ LNPNP 1651_ SERIL 1656_ ISDAK 1661_ GILQC 1666_ LLWGP 1671_ REDLF 1676_ QTFTA 1681_ CPSLV 1686_ QRNTL 1691_ LQNWL 1696_ DIKRT 1701_ LLMIK 1706_ FAEKS 1711_ LDREG 1716_ GISLE 1721_ DWLCA 1726_ QYLAF 1731_ ATTDS 1736_ LSCIV 1741_KILQH
1: Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics (PubMed:20534451, PubMed:23105102, PubMed:35687021). Acts as a scaffold for mediating EGFR signaling (PubMed:23846654)