Gene name: MVB12B

Uniprot entry:

Q9H7P6

Protein names:

Multivesicular body subunit 12B (ESCRT-I complex subunit MVB12B) (Protein FAM125B)

Protein sequence:

1_MRSCF 6_ CVRRS 11_ RDPPP 16_ PQPPP 21_ PPPQR 26_ GTDQS 31_ TMPEV 36_ KDLSE 41_ ALPET 46_ SMDPI 51_ TGVGV 56_ VASRN 61_ RAPTG 66_ YDVVA 71_ QTADG 76_ VDADL 81_ WKDGL 86_ FKSKV 91_ TRYLC 96_ FTRSF 101_ SKENS 106_ HLGNV 111_ LVDMK 116_ LIDIK 121_ DTLPV 126_ GFIPI 131_ QETVD 136_ TQEVA 141_ FRKKR 146_ LCIKF 151_ IPRDS 156_ TEAAI 161_ CDIRI 166_ MGRTK 171_ QAPPQ 176_ YTFIG 181_ ELNSM 186_ GIWYR 191_ MGRVP 196_ RNHDS 201_ SQPTT 206_ PSQSS 211_ AASTP 216_ APNLP 221_ RHISL 226_ TLPAT 231_ FRGRN 236_ STRTD 241_ YEYQH 246_ SNLYA 251_ ISAMD 256_ GVPFM 261_ ISEKF 266_ SCVPE 271_ SMQPF 276_ DLLGI 281_ TIKSL 286_ AEIEK 291_ EYEYS 296_ FRTEQ 301_ SAAAR 306_ LPPSP 311_TRCQQ

Protein annotations

Protein functions:

1: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies