Transducin-like enhancer protein 6
1_MTSRD 6_ QPRPK 11_ GPPKS 16_ TSPCP 21_ GISNS 26_ ESSPT 31_ LNYQG 36_ ILNRL 41_ KQFPR 46_ FSPHF 51_ AAELE 56_ SIYYS 61_ LHKIQ 66_ QDVAE 71_ HHKQI 76_ GNVLQ 81_ IVESC 86_ SQLQG 91_ FQSEE 96_ VSPAE 101_ PASPG 106_ TPQQV 111_ KDKTL 116_ QESSF 121_ EDIMA 126_ TRSSD 131_ WLRRP 136_ LGEDN 141_ QPETQ 146_ LFWDK 151_ EPWFW 156_ HDTLT 161_ EQLWR 166_ IFAGV 171_ HDEKA 176_ KPRDR 181_ QQAPG 186_ LGQES 191_ KAPGS 196_ CDPGT 201_ DPCPE 206_ DASTP 211_ RPPEA 216_ SSSPP 221_ EGSQD 226_ RNTSW 231_ GVVQE 236_ PPGRA 241_ SRFLQ 246_ SISWD 251_ PEDFE 256_ DAWKR 261_ PDALP 266_ GQSKR 271_ LAVPC 276_ KLEKM 281_ RILAH 286_ GELVL 291_ ATAIS 296_ SFTRH 301_ VFTCG 306_ RRGIK 311_ VWSLT 316_ GQVAE 321_ DRFPE 326_ SHLPI 331_ QTPGA 336_ FLRTC 341_ LLSSN 346_ SRSLL 351_ TGGYN 356_ LASVS 361_ VWDLA 366_ APSLH 371_ VKEQL 376_ PCAGL 381_ NCQAL 386_ DANLD 391_ ANLAF 396_ ASFTS 401_ GVVRI 406_ WDLRD 411_ QSVVR 416_ DLKGY 421_ PDGVK 426_ SIVVK 431_ GYNIW 436_ TGGPD 441_ ACLRC 446_ WDQRT 451_ IMKPL 456_ EYQFK 461_ SQIMS 466_ LSHSP 471_ QEDWV 476_ LLGMA 481_ NGQQW 486_ LQSTS 491_ GSQRH 496_ MVGQK 501_ DSVIL 506_ SVKFS 511_ PFGQW 516_ WASVG 521_ MDDFL 526_ GVYSM 531_ PAGTK 536_ VFEVP 541_ EMSPV 546_ TCCDV 551_ SSNNR 556_ LVVTG 561_ SGEHA 566_SVYQI
1: Component of the subcortical maternal complex (SCMC), a multiprotein complex that plays a key role in early embryonic development (PubMed:26537248). The SCMC complex is a structural constituent of cytoplasmic lattices, which consist in fibrous structures found in the cytoplasm of oocytes and preimplantation embryos (By similarity). They are required to store maternal proteins critical for embryonic development, such as proteins that control epigenetic reprogramming of the preimplantation embryo, and prevent their degradation or activation (By similarity). Also required for spermatogenesis: regulates spermatogonia proliferation and cell cycle progression, potentially via regulation of cell cycle regulatory genes such as; CEBPB, CEBPA, CSF3, PCNA, and CDK4 (By similarity). Suppresses FOXG1/BF-1-mediated transcriptional repression by inhibiting interaction of the transcriptional corepressor TLE1 with FOXG1 which promotes cortical neuron differentiation (By similarity). Acts as a transcriptional corepressor of NFATC1-mediated gene expression by contributing to PAX6-mediated repression (By similarity)
2: Component of the subcortical maternal complex (SCMC), a multiprotein complex that plays a key role in early embryonic development