Gene name: VCPKMT

Uniprot entry:

Q9H867

Protein names:

Protein N-lysine methyltransferase METTL21D (EC 2.1.1.-) (Methyltransferase-like protein 21D) (VCP lysine methyltransferase) (VCP-KMT) (Valosin-containing protein lysine methyltransferase)

Protein sequence:

1_MADTL 6_ ESSLE 11_ DPLRS 16_ FVRVL 21_ EKRDG 26_ TVLRL 31_ QQYSS 36_ GGVGC 41_ VVWDA 46_ AIVLS 51_ KYLET 56_ PEFSG 61_ DGAHA 66_ LSRRS 71_ VLELG 76_ SGTGA 81_ VGLMA 86_ ATLGA 91_ DVVVT 96_ DLEEL 101_ QDLLK 106_ MNINM 111_ NKHLV 116_ TGSVQ 121_ AKVLK 126_ WGEEI 131_ EGFPS 136_ PPDFI 141_ LMADC 146_ IYYEE 151_ SLEPL 156_ LKTLK 161_ DISGF 166_ ETCII 171_ CCYEQ 176_ RTMGK 181_ NPEIE 186_ KKYFE 191_ LLQLD 196_ FDFEK 201_ IPLEK 206_ HDEEY 211_ RSEDI 216_ HIIYI 221_RKKKS

Protein annotations

Protein functions:

1: Protein N-lysine methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity