Gene name: DDX31

Uniprot entry:

Q9H8H2

Protein names:

Probable ATP-dependent RNA helicase DDX31 (EC 3.6.4.13) (DEAD box protein 31) (Helicain)

Protein sequence:

1_MAPDL 6_ ASQRH 11_ SESFP 16_ SVNSR 21_ PNVIL 26_ PGREG 31_ RREGL 36_ PPGGG 41_ TRGSL 46_ VPTRP 51_ VPPSP 56_ APLGT 61_ SPYSW 66_ SRSGP 71_ GRGGG 76_ AGSSR 81_ VPRGV 86_ PGPAV 91_ CAPGS 96_ LLHHA 101_ SPTQT 106_ MAAAD 111_ GSLFD 116_ NPRTF 121_ SRRPP 126_ AQASR 131_ QAKAT 136_ KRKYQ 141_ ASSEA 146_ PPAKR 151_ RNETS 156_ FLPAK 161_ KTSVK 166_ ETQRT 171_ FKGNA 176_ QKMFS 181_ PKKHS 186_ VSTSD 191_ RNQEE 196_ RQCIK 201_ TSSLF 206_ KNNPD 211_ IPELH 216_ RPVVK 221_ QVQEK 226_ VFTSA 231_ AFHEL 236_ GLHPH 241_ LISTI 246_ NTVLK 251_ MSSMT 256_ SVQKQ 261_ SIPVL 266_ LEGRD 271_ ALVRS 276_ QTGSG 281_ KTLAY 286_ CIPVV 291_ QSLQA 296_ MESKI 301_ QRSDG 306_ PYALV 311_ LVPTR 316_ ELALQ 321_ SFDTV 326_ QKLLK 331_ PFTWI 336_ VPGVL 341_ MGGEK 346_ RKSEK 351_ ARLRK 356_ GINIL 361_ ISTPG 366_ RLVDH 371_ IKSTK 376_ NIHFS 381_ RLRWL 386_ VFDEA 391_ DRILD 396_ LGFEK 401_ DITVI 406_ LNAVN 411_ AECQK 416_ RQNVL 421_ LSATL 426_ TEGVT 431_ RLADI 436_ SLHDP 441_ VSISV 446_ LDKSH 451_ DQLNP 456_ KDKAV 461_ QEVCP 466_ PPAGD 471_ KLDSF 476_ AIPES 481_ LKQHV 486_ TVVPS 491_ KLRLV 496_ CLAAF 501_ ILQKC 506_ KFEED 511_ QKMVV 516_ FFSSC 521_ ELVEF 526_ HYSLF 531_ LQTLL 536_ SSSGA 541_ PASGQ 546_ LPSAS 551_ MRLKF 556_ LRLHG 561_ GMEQE 566_ ERTAV 571_ FQEFS 576_ HSRRG 581_ VLLCT 586_ DVAAR 591_ GLDLP 596_ QVTWI 601_ VQYNA 606_ PSSPA 611_ EYIHR 616_ IGRTA 621_ RIGCH 626_ GSSLL 631_ ILAPS 636_ EAEYV 641_ NSLAS 646_ HKINV 651_ SEIKM 656_ EDILC 661_ VLTRD 666_ DCFKG 671_ KRWGA 676_ QKSHA 681_ VGPQE 686_ IRERA 691_ TVLQT 696_ VFEDY 701_ VHSSE 706_ RRVSW 711_ AKKAL 716_ QSFIQ 721_ AYATY 726_ PRELK 731_ HIFHV 736_ RSLHL 741_ GHVAK 746_ SFGLR 751_ DAPRN 756_ LSALT 761_ RKKRK 766_ AHVKR 771_ PDLHK 776_ KTQSK 781_ HSLAE 786_ ILRSE 791_ YSSGM 796_ EADIA 801_ KVKKQ 806_ NAPGE 811_ PGGRP 816_ LQHSL 821_ QPTPC 826_ FGRGK 831_ TLKWR 836_ KTQKG 841_ VQRDS 846_KTSQK

Protein annotations

Protein functions:

1: May have DNA helicase activity and RNA helicase activity. Probably have ssDNA and RNA dependent ATPase activity (By similarity). Plays a role in ribosome biogenesis and TP53/p53 regulation through its interaction with NPM1 (PubMed:23019224)