Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2) (Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains) (EAPF) (PH and FYVE domain-containing protein 2) (Phafin-2) (Phafin2) (Zinc finger FYVE domain-containing protein 18)
1_MVDRL 6_ ANSEA 11_ NTRRI 16_ SIVEN 21_ CFGAA 26_ GQPLT 31_ IPGRV 36_ LIGEG 41_ VLTKL 46_ CRKKP 51_ KARQF 56_ FLFND 61_ ILVYG 66_ NIVIQ 71_ KKKYN 76_ KQHII 81_ PLENV 86_ TIDSI 91_ KDEGD 96_ LRNGW 101_ LIKTP 106_ TKSFA 111_ VYAAT 116_ ATEKS 121_ EWMNH 126_ INKCV 131_ TDLLS 136_ KSGKT 141_ PSNEH 146_ AAVWV 151_ PDSEA 156_ TVCMR 161_ CQKAK 166_ FTPVN 171_ RRHHC 176_ RKCGF 181_ VVCGP 186_ CSEKR 191_ FLLPS 196_ QSSKP 201_ VRICD 206_ FCYDL 211_ LSAGD 216_ MATCQ 221_ PARSD 226_ SYSQS 231_ LKSPL 236_ NDMSD 241_DDDDD
1: May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467)