Gene name: JPT2

Uniprot entry:

Q9H910

Protein names:

Jupiter microtubule associated homolog 2 (Hematological and neurological expressed 1-like protein) (HN1-like protein)

Protein sequence:

1_MFQVP 6_ DSEGG 11_ RAGSR 16_ AMKPP 21_ GGESS 26_ NLFGS 31_ PEEAT 36_ PSSRP 41_ NRMAS 46_ NIFGP 51_ TEEPQ 56_ NIPKR 61_ TNPPG 66_ GKGSG 71_ IFDES 76_ TPVQT 81_ RQHLN 86_ PPGGK 91_ TSDIF 96_ GSPVT 101_ ATSRL 106_ AHPNK 111_ PKDHV 116_ FLCEG 121_ EEPKS 126_ DLKAA 131_ RSIPA 136_ GAEPG 141_ EKGSA 146_ RKAGP 151_ AKEQE 156_ PMPTV 161_ DSHEP 166_ RLGPR 171_ PRSHN 176_ KVLNP 181_PGGKS

Protein annotations

Protein functions:

1: Nicotinic acid adenine dinucleotide phosphate (NAADP) binding protein required for NAADP-evoked intracellular calcium release (PubMed:33758061, PubMed:33758062). Confers NAADP-sensitivity to the two pore channels (TPCs) complex (PubMed:33758061). Enables NAADP to activate Ca(2+) release from the endoplasmic reticulum through ryanodine receptors (PubMed:33758062)

2: (Microbial infection) Involved in the endolysosomal trafficking of human coronavirus SARS-CoV-2