RecQ-mediated genome instability protein 1 (BLM-associated protein of 75 kDa) (BLAP75) (FAAP75)
1_MNVTS 6_ IALRA 11_ ETWLL 16_ AAWHV 21_ KVPPM 26_ WLEAC 31_ INWIQ 36_ EENNN 41_ VNLSQ 46_ AQMNK 51_ QVFEQ 56_ WLLTD 61_ LRDLE 66_ HPLLP 71_ DGILE 76_ IPKGE 81_ LNGFY 86_ ALQIN 91_ SLVDV 96_ SQPAY 101_ SQIQK 106_ LRGKN 111_ TTNDL 116_ VTAEA 121_ QVTPK 126_ PWEAK 131_ PSRML 136_ MLQLT 141_ DGIVQ 146_ IQGME 151_ YQPIP 156_ ILHSD 161_ LPPGT 166_ KILIY 171_ GNISF 176_ RLGVL 181_ LLKPE 186_ NVKVL 191_ GGEVD 196_ ALLEE 201_ YAQEK 206_ VLARL 211_ IGEPD 216_ LVVSV 221_ IPNNS 226_ NENIP 231_ RVTDV 236_ LDPAL 241_ GPSDE 246_ ELLAS 251_ LDEND 256_ ELTAN 261_ NDTSS 266_ ERCFT 271_ TGSSS 276_ NTIPT 281_ RQSSF 286_ EPEFV 291_ ISPRP 296_ KEEPS 301_ NLSIH 306_ VMDGE 311_ LDDFS 316_ LEEAL 321_ LLEET 326_ VQKEQ 331_ METKE 336_ LQPLT 341_ FNRNA 346_ DRSIE 351_ RFSHN 356_ PNTTN 361_ NFSLT 366_ CKNGN 371_ NNWSE 376_ KNVSE 381_ QMTNE 386_ DKSFG 391_ CPSVR 396_ DQNRS 401_ IFSVH 406_ CNVPL 411_ AHDFT 416_ NKEKN 421_ LETDN 426_ KIKQT 431_ SSSDS 436_ HSLNN 441_ KILNR 446_ EVVNY 451_ VQKRN 456_ SQISN 461_ ENDCN 466_ LQSCS 471_ LRSSE 476_ NSINL 481_ SIAMD 486_ LYSPP 491_ FVYLS 496_ VLMAS 501_ KPKEV 506_ TTVKV 511_ KAFIV 516_ TLTGN 521_ LSSSG 526_ GIWSI 531_ TAKVS 536_ DGTAY 541_ LDVDF 546_ VDEIL 551_ TSLIG 556_ FSVPE 561_ MKQSK 566_ KDPLQ 571_ YQKFL 576_ EGLQK 581_ CQRDL 586_ IDLCC 591_ LMTIS 596_ FNPSL 601_ SKAMV 606_ LALQD 611_ VNMEH 616_LENLK
1: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability