Protein transport protein Sec61 subunit alpha isoform 2 (Sec61 alpha-2)
1_MGIKF 6_ LEVIK 11_ PFCAV 16_ LPEIQ 21_ KPERK 26_ IQFRE 31_ KVLWT 36_ AITLF 41_ IFLVC 46_ CQIPL 51_ FGIMS 56_ SDSAD 61_ PFYWM 66_ RVILA 71_ SNRGT 76_ LMELG 81_ ISPIV 86_ TSGLI 91_ MQLLA 96_ GAKII 101_ EVGDT 106_ PKDRA 111_ LFNGA 116_ QKLFG 121_ MIITI 126_ GQAIV 131_ YVMTG 136_ MYGDP 141_ AEMGA 146_ GICLL 151_ IIIQL 156_ FVAGL 161_ IVLLL 166_ DELLQ 171_ KGYGL 176_ GSGIS 181_ LFIAT 186_ NICET 191_ IVWKA 196_ FSPTT 201_ INTGR 206_ GTEFE 211_ GAVIA 216_ LFHLL 221_ ATRTD 226_ KVRAL 231_ REAFY 236_ RQNLP 241_ NLMNL 246_ IATVF 251_ VFAVV 256_ IYFQG 261_ FRVDL 266_ PIKSA 271_ RYRGQ 276_ YSSYP 281_ IKLFY 286_ TSNIP 291_ IILQS 296_ ALVSN 301_ LYVIS 306_ QMLSV 311_ RFSGN 316_ FLVNL 321_ LGQWA 326_ DVSGG 331_ GPARS 336_ YPVGG 341_ LCYYL 346_ SPPES 351_ MGAIF 356_ EDPVH 361_ VVVYI 366_ IFMLG 371_ SCAFF 376_ SKTWI 381_ EVSGS 386_ SAKDV 391_ AKQLK 396_ EQQMV 401_ MRGHR 406_ DTSMV 411_ HELNR 416_ YIPTA 421_ AAFGG 426_ LCIGA 431_ LSVLA 436_ DFLGA 441_ IGSGT 446_ GILLA 451_ VTIIY 456_ QYFEI 461_ FVKEQ 466_ AEVGG 471_MGALF
1: Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides