Probable cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)
1_MLRTT 6_ RGPGL 11_ GPPLL 16_ QAALG 21_ LGRAG 26_ WHWPA 31_ GRAAS 36_ GGRGR 41_ AWLQP 46_ TGRET 51_ GVQVY 56_ NSLTG 61_ RKEPL 66_ IVAHA 71_ EAASW 76_ YSCGP 81_ TVYDH 86_ AHLGH 91_ ACSYV 96_ RFDII 101_ RRILT 106_ KVFGC 111_ SIVMV 116_ MGITD 121_ VDDKI 126_ IKRAN 131_ EMNIS 136_ PASLA 141_ SLYEE 146_ DFKQD 151_ MAALK 156_ VLPPT 161_ VYLRV 166_ TENIP 171_ QIISF 176_ IEGII 181_ ARGNA 186_ YSTAK 191_ GNVYF 196_ DLKSR 201_ GDKYG 206_ KLVGV 211_ VPGPV 216_ GEPAD 221_ SDKRH 226_ ASDFA 231_ LWKAA 236_ KPQEV 241_ FWASP 246_ WGPGR 251_ PGWHI 256_ ECSAI 261_ ASMVF 266_ GSQLD 271_ IHSGG 276_ IDLAF 281_ PHHEN 286_ EIAQC 291_ EVFHQ 296_ CEQWG 301_ NYFLH 306_ SGHLH 311_ AKGKE 316_ EKMSK 321_ SLKNY 326_ ITIKD 331_ FLKTF 336_ SPDVF 341_ RFFCL 346_ RSSYR 351_ SAIDY 356_ SDSAM 361_ LQAQQ 366_ LLLGL 371_ GSFLE 376_ DARAY 381_ MKGQL 386_ ACGSV 391_ REAML 396_ WERLS 401_ STKRA 406_ VKAAL 411_ ADDFD 416_ TPRVV 421_ DAILG 426_ LAHHG 431_ NGQLR 436_ ASLKE 441_ PEGPR 446_ SPAVF 451_ GAIIS 456_ YFEQF 461_ FETVG 466_ ISLAN 471_ QQYVS 476_ GDGSE 481_ ATLHG 486_ VVDEL 491_ VRFRQ 496_ KVRQF 501_ ALAMP 506_ EATGD 511_ ARRQQ 516_ LLERQ 521_ PLLEA 526_ CDTLR 531_ RGLTA 536_ HGINI 541_ KDRSS 546_ TTSTW 551_ ELLDQ 556_RTKDQ
1: Mitochondrial cysteine-specific aminoacyl-tRNA synthetase that catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys)
2: In addition to its role as an aminoacyl-tRNA synthetase, has also cysteine persulfide synthase activity. Produces reactive persulfide species such as cysteine persulfide (CysSSH) from substrate cysteine and mediate direct incorporation of CysSSH into proteins during translations, resulting in protein persulfides and polysulfides (PubMed:29079736). CysSSHs behave as potent antioxidants and cellular protectants (PubMed:29079736)