Gene name: CERS4

Uniprot entry:

Q9HA82

Protein names:

Ceramide synthase 4 (CerS4) (EC 2.3.1.-) (LAG1 longevity assurance homolog 4) (Sphingosine N-acyltransferase CERS4) (EC 2.3.1.24)

Protein sequence:

1_MLSSF 6_ NEWFW 11_ QDRFW 16_ LPPNV 21_ TWTEL 26_ EDRDG 31_ RVYPH 36_ PQDLL 41_ AALPL 46_ ALVLL 51_ AMRLA 56_ FERFI 61_ GLPLS 66_ RWLGV 71_ RDQTR 76_ RQVKP 81_ NATLE 86_ KHFLT 91_ EGHRP 96_ KEPQL 101_ SLLAA 106_ QCGLT 111_ LQQTQ 116_ RWFRR 121_ RRNQD 126_ RPQLT 131_ KKFCE 136_ ASWRF 141_ LFYLS 146_ SFVGG 151_ LSVLY 156_ HESWL 161_ WAPVM 166_ CWDRY 171_ PNQTL 176_ KPSLY 181_ WWYLL 186_ ELGFY 191_ LSLLI 196_ RLPFD 201_ VKRKD 206_ FKEQV 211_ IHHFV 216_ AVILM 221_ TFSYS 226_ ANLLR 231_ IGSLV 236_ LLLHD 241_ SSDYL 246_ LEACK 251_ MVNYM 256_ QYQQV 261_ CDALF 266_ LIFSF 271_ VFFYT 276_ RLVLF 281_ PTQIL 286_ YTTYY 291_ ESISN 296_ RGPFF 301_ GYYFF 306_ NGLLM 311_ LLQLL 316_ HVFWS 321_ CLILR 326_ MLYSF 331_ MKKGQ 336_ MEKDI 341_ RSDVE 346_ ESDSS 351_ EEAAA 356_ AQEPL 361_ QLKNG 366_ AAGGP 371_ RPAPT 376_ DGPRS 381_ RVAGR 386_LTNRH

Protein annotations

Protein functions:

1: Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl donor