Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (Putative heme chaperone)
1_MALPG 6_ ARARG 11_ WAAAA 16_ RAAQR 21_ RRRVE 26_ NAGGS 31_ PSPEP 36_ AGRRA 41_ ALYVH 46_ WPYCE 51_ KRCSY 56_ CNFNK 61_ YIPRR 66_ LEEAA 71_ MQKCL 76_ VTEAQ 81_ TLLRL 86_ SGVQR 91_ VESVF 96_ FGGGT 101_ PSLAS 106_ PHTVA 111_ AVLEA 116_ VAQAA 121_ HLPAD 126_ LEVTL 131_ EANPT 136_ SAPGS 141_ RLAEF 146_ GAAGV 151_ NRLSI 156_ GLQSL 161_ DDTEL 166_ RLLGR 171_ THSAC 176_ DALRT 181_ LAEAR 186_ RLFPG 191_ RVSVD 196_ LMLGL 201_ PAQQV 206_ GPWLG 211_ QLQEL 216_ LHHCD 221_ DHLSL 226_ YQLSL 231_ ERGTA 236_ LFAQV 241_ QRGAL 246_ PAPDP 251_ ELAAE 256_ MYQRG 261_ RAVLR 266_ EAGFH 271_ QYEVS 276_ NFARN 281_ GALST 286_ HNWTY 291_ WQCGQ 296_ YLGVG 301_ PGAHG 306_ RFMPQ 311_ GAGGH 316_ TREAR 321_ IQTLE 326_ PDNWM 331_ KEVML 336_ FGHGT 341_ RKRVP 346_ LGRLE 351_ LLEEV 356_ LALGL 361_ RTDVG 366_ ITHQH 371_ WQQFE 376_ PQLTL 381_ WDVFG 386_ ANKEV 391_ QELLE 396_ RGLLQ 401_ LDHRG 406_ LRCSW 411_ EGLAV 416_ LDSLL 421_ LTLLP 426_ QLQEA 431_ WQQRT 436_PSPVP
1: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity (Probable). Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (By similarity)