Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (hCNT3)
1_MELRS 6_ TAAPR 11_ AEGYS 16_ NVGFQ 21_ NEENF 26_ LENEN 31_ TSGNN 36_ SIRSR 41_ AVQSR 46_ EHTNT 51_ KQDEE 56_ QVTVE 61_ QDSPR 66_ NREHM 71_ EDDDE 76_ EMQQK 81_ GCLER 86_ RYDTV 91_ CGFCR 96_ KHKTT 101_ LRHII 106_ WGILL 111_ AGYLV 116_ MVISA 121_ CVLNF 126_ HRALP 131_ LFVIT 136_ VAAIF 141_ FVVWD 146_ HLMAK 151_ YEHRI 156_ DEMLS 161_ PGRRL 166_ LNSHW 171_ FWLKW 176_ VIWSS 181_ LVLAV 186_ IFWLA 191_ FDTAK 196_ LGQQQ 201_ LVSFG 206_ GLIMY 211_ IVLLF 216_ LFSKY 221_ PTRVY 226_ WRPVL 231_ WGIGL 236_ QFLLG 241_ LLILR 246_ TDPGF 251_ IAFDW 256_ LGRQV 261_ QTFLE 266_ YTDAG 271_ ASFVF 276_ GEKYK 281_ DHFFA 286_ FKVLP 291_ IVVFF 296_ STVMS 301_ MLYYL 306_ GLMQW 311_ IIRKV 316_ GWIML 321_ VTTGS 326_ SPIES 331_ VVASG 336_ NIFVG 341_ QTESP 346_ LLVRP 351_ YLPYI 356_ TKSEL 361_ HAIMT 366_ AGFST 371_ IAGSV 376_ LGAYI 381_ SFGVP 386_ SSHLL 391_ TASVM 396_ SAPAS 401_ LAAAK 406_ LFWPE 411_ TEKPK 416_ ITLKN 421_ AMKME 426_ SGDSG 431_ NLLEA 436_ ATQGA 441_ SSSIS 446_ LVANI 451_ AVNLI 456_ AFLAL 461_ LSFMN 466_ SALSW 471_ FGNMF 476_ DYPQL 481_ SFELI 486_ CSYIF 491_ MPFSF 496_ MMGVE 501_ WQDSF 506_ MVARL 511_ IGYKT 516_ FFNEF 521_ VAYEH 526_ LSKWI 531_ HLRKE 536_ GGPKF 541_ VNGVQ 546_ QYISI 551_ RSEII 556_ ATYAL 561_ CGFAN 566_ IGSLG 571_ IVIGG 576_ LTSMA 581_ PSRKR 586_ DIASG 591_ AVRAL 596_ IAGTV 601_ ACFMT 606_ ACIAG 611_ ILSST 616_ PVDIN 621_ CHHVL 626_ ENAFN 631_ STFPG 636_ NTTKV 641_ IACCQ 646_ SLLSS 651_ TVAKG 656_ PGEVI 661_ PGGNH 666_ SLYSL 671_ KGCCT 676_ LLNPS 681_ TFNCN 686_GISNT
1: Sodium-dependent, pyrimidine- and purine-selective (PubMed:11032837, PubMed:15861042, PubMed:16446384, PubMed:17140564, PubMed:21998139). Involved in the homeostasis of endogenous nucleosides (PubMed:11032837, PubMed:15861042). Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine) (PubMed:11032837). Employs a 2:1 sodium/nucleoside ratio (PubMed:11032837). Transports uridine (PubMed:21795683). Also able to transport gemcitabine, 3'-azido-3'-deoxythymidine (AZT), ribavirin and 3-deazauridine (PubMed:11032837, PubMed:17140564)