Gene name: EDA2R

Uniprot entry:

Q9HAV5

Protein names:

Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor)

Protein sequence:

1_MDCQE 6_ NEYWD 11_ QWGRC 16_ VTCQR 21_ CGPGQ 26_ ELSKD 31_ CGYGE 36_ GGDAY 41_ CTACP 46_ PRRYK 51_ SSWGH 56_ HRCQS 61_ CITCA 66_ VINRV 71_ QKVNC 76_ TATSN 81_ AVCGD 86_ CLPRF 91_ YRKTR 96_ IGGLQ 101_ DQECI 106_ PCTKQ 111_ TPTSE 116_ VQCAF 121_ QLSLV 126_ EADTP 131_ TVPPQ 136_ EATLV 141_ ALVSS 146_ LLVVF 151_ TLAFL 156_ GLFFL 161_ YCKQF 166_ FNRHC 171_ QRGGL 176_ LQFEA 181_ DKTAK 186_ EESLF 191_ PVPPS 196_ KETSA 201_ ESQVS 206_ ENIFQ 211_ TQPLN 216_ PILED 221_ DCSST 226_ SGFPT 231_ QESFT 236_ MASCT 241_ SESHS 246_ HWVHS 251_ PIECT 256_ ELDLQ 261_ KFSSS 266_ ASYTG 271_ AETLG 276_ GNTVE 281_ STGDR 286_ LELNV 291_PFEVP

Protein annotations

Protein functions:

1: Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6