Transcription factor IIIB 50 kDa subunit (TFIIIB50) (hTFIIIB50) (B-related factor 2) (BRF-2) (hBRFU)
1_MPGRG 6_ RCPDC 11_ GSTEL 16_ VEDSH 21_ YSQSQ 26_ LVCSD 31_ CGCVV 36_ TEGVL 41_ TTTFS 46_ DEGNL 51_ REVTY 56_ SRSTG 61_ ENEQV 66_ SRSQQ 71_ RGLRR 76_ VRDLC 81_ RVLQL 86_ PPTFE 91_ DTAVA 96_ YYQQA 101_ YRHSG 106_ IRAAR 111_ LQKKE 116_ VLVGC 121_ CVLIT 126_ CRQHN 131_ WPLTM 136_ GAICT 141_ LLYAD 146_ LDVFS 151_ STYMQ 156_ IVKLL 161_ GLDVP 166_ SLCLA 171_ ELVKT 176_ YCSSF 181_ KLFQA 186_ SPSVP 191_ AKYVE 196_ DKEKM 201_ LSRTM 206_ QLVEL 211_ ANETW 216_ LVTGR 221_ HPLPV 226_ ITAAT 231_ FLAWQ 236_ SLQPA 241_ DRLSC 246_ SLARF 251_ CKLAN 256_ VDLPY 261_ PASSR 266_ LQELL 271_ AVLLR 276_ MAEQL 281_ AWLRV 286_ LRLDK 291_ RSVVK 296_ HIGDL 301_ LQHRQ 306_ SLVRS 311_ AFRDG 316_ TAEVE 321_ TREKE 326_ PPGWG 331_ QGQGE 336_ GEVGN 341_ NSLGL 346_ PQGKR 351_ PASPA 356_ LLLPP 361_ CMLKS 366_ PKRIC 371_ PVPPV 376_ STVTG 381_ DENIS 386_ DSEIE 391_ QYLRT 396_ PQEVR 401_ DFQRA 406_ QAARQ 411_AATSV
1: General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites (PubMed:11040218, PubMed:11121026, PubMed:11564744, PubMed:26638071). Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress (PubMed:26638071). Down-regulates expression of target genes in response to oxidative stress (PubMed:26638071). Overexpression protects cells against apoptosis in response to oxidative stress (PubMed:26638071)