Transcription initiation factor TFIID subunit 9B (Neuronal cell death-related protein 7) (DN-7) (Transcription initiation factor TFIID subunit 9-like) (Transcription-associated factor TAFII31L)
1_MESGK 6_ MAPPK 11_ NAPRD 16_ ALVMA 21_ QILKD 26_ MGITE 31_ YEPRV 36_ INQML 41_ EFAFR 46_ YVTTI 51_ LDDAK 56_ IYSSH 61_ AKKPN 66_ VDADD 71_ VRLAI 76_ QCRAD 81_ QSFTS 86_ PPPRD 91_ FLLDI 96_ ARQKN 101_ QTPLP 106_ LIKPY 111_ AGPRL 116_ PPDRY 121_ CLTAP 126_ NYRLK 131_ SLIKK 136_ GPNQG 141_ RLVPR 146_ LSVGA 151_ VSSKP 156_ TTPTI 161_ ATPQT 166_ VSVPN 171_ KVATP 176_ MSVTS 181_ QRFTV 186_ QIPPS 191_ QSTPV 196_ KPVPA 201_ TTAVQ 206_ NVLIN 211_ PSMIG 216_ PKNIL 221_ ITTNM 226_ VSSQN 231_ TANEA 236_ NPLKR 241_ KHEDD 246_DDNDI
1: Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription