Lysophosphatidic acid receptor 2 (LPA receptor 2) (LPA-2) (Lysophosphatidic acid receptor Edg-4)
1_MGQCY 6_ YNETI 11_ GFFYN 16_ NSGKE 21_ LSSHW 26_ RPKDV 31_ VVVAL 36_ GLTVS 41_ VLVLL 46_ TNLLV 51_ IAAIA 56_ SNRRF 61_ HQPIY 66_ YLLGN 71_ LAAAD 76_ LFAGV 81_ AYLFL 86_ MFHTG 91_ PRTAR 96_ LSLEG 101_ WFLRQ 106_ GLLDT 111_ SLTAS 116_ VATLL 121_ AIAVE 126_ RHRSV 131_ MAVQL 136_ HSRLP 141_ RGRVV 146_ MLIVG 151_ VWVAA 156_ LGLGL 161_ LPAHS 166_ WHCLC 171_ ALDRC 176_ SRMAP 181_ LLSRS 186_ YLAVW 191_ ALSSL 196_ LVFLL 201_ MVAVY 206_ TRIFF 211_ YVRRR 216_ VQRMA 221_ EHVSC 226_ HPRYR 231_ ETTLS 236_ LVKTV 241_ VIILG 246_ AFVVC 251_ WTPGQ 256_ VVLLL 261_ DGLGC 266_ ESCNV 271_ LAVEK 276_ YFLLL 281_ AEANS 286_ LVNAA 291_ VYSCR 296_ DAEMR 301_ RTFRR 306_ LLCCA 311_ CLRQS 316_ TRESV 321_ HYTSS 326_ AQGGA 331_ STRIM 336_ LPENG 341_HPLMD
1: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation