GPN-loop GTPase 1 (EC 3.6.5.-) (MBD2-interacting protein) (MBDin) (RNAPII-associated protein 4) (XPA-binding protein 1)
1_MAASA 6_ AAAEL 11_ QASGG 16_ PRHPV 21_ CLLVL 26_ GMAGS 31_ GKTTF 36_ VQRLT 41_ GHLHA 46_ QGTPP 51_ YVINL 56_ DPAVH 61_ EVPFP 66_ ANIDI 71_ RDTVK 76_ YKEVM 81_ KQYGL 86_ GPNGG 91_ IVTSL 96_ NLFAT 101_ RFDQV 106_ MKFIE 111_ KAQNM 116_ SKYVL 121_ IDTPG 126_ QIEVF 131_ TWSAS 136_ GTIIT 141_ EALAS 146_ SFPTV 151_ VIYVM 156_ DTSRS 161_ TNPVT 166_ FMSNM 171_ LYACS 176_ ILYKT 181_ KLPFI 186_ VVMNK 191_ TDIID 196_ HSFAV 201_ EWMQD 206_ FEAFQ 211_ DALNQ 216_ ETTYV 221_ SNLTR 226_ SMSLV 231_ LDEFY 236_ SSLRV 241_ VGVSA 246_ VLGTG 251_ LDELF 256_ VQVTS 261_ AAEEY 266_ EREYR 271_ PEYER 276_ LKKSL 281_ ANAES 286_ QQQRE 291_ QLERL 296_ RKDMG 301_ SVALD 306_ AGTAK 311_ DSLSP 316_ VLHPS 321_ DLILT 326_ RGTLD 331_ EEDEE 336_ ADSDT 341_ DDIDH 346_ RVTEE 351_ SHEEP 356_ AFQNF 361_ MQESM 366_AQYWK
1: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119)