High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein 1) (HMG domain-containing protein HMGX1)
1_MENLM 6_ TSSTL 11_ PPLFA 16_ DEDGS 21_ KESND 26_ LATTG 31_ LNHPE 36_ VPYSS 41_ GATSS 46_ TNNPE 51_ FVEDL 56_ SQGQL 61_ LQSES 66_ SNAAE 71_ GNEQR 76_ HEDEQ 81_ RSKRG 86_ GWSKG 91_ RKRKK 96_ PLRDS 101_ NAPKS 106_ PLTGY 111_ VRFMN 116_ ERREQ 121_ LRAKR 126_ PEVPF 131_ PEITR 136_ MLGNE 141_ WSKLP 146_ PEEKQ 151_ RYLDE 156_ ADRDK 161_ ERYMK 166_ ELEQY 171_ QKTEA 176_ YKVFS 181_ RKTQD 186_ RQKGK 191_ SHRQD 196_ AARQA 201_ THDHE 206_ KETEV 211_ KERSV 216_ FDIPI 221_ FTEEF 226_ LNHSK 231_ AREAE 236_ LRQLR 241_ KSNME 246_ FEERN 251_ AALQK 256_ HVESM 261_ RTAVE 266_ KLEVD 271_ VIQER 276_ SRNTV 281_ LQQHL 286_ ETLRQ 291_ VLTSS 296_ FASMP 301_ LPGSG 306_ ETPTV 311_ DTIDS 316_ YMNRL 321_ HSIIL 326_ ANPQD 331_ NENFI 336_ ATVRE 341_VVNRL
1: Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4 (By similarity)