Sodium- and chloride-dependent transporter XTRP3 (Sodium/imino-acid transporter 1) (Solute carrier family 6 member 20) (Transporter rB21A homolog)
1_MEKAR 6_ PLWAN 11_ SLQFV 16_ FACIS 21_ YAVGL 26_ GNVWR 31_ FPYLC 36_ QMYGG 41_ GSFLV 46_ PYIIM 51_ LIVEG 56_ MPLLY 61_ LELAV 66_ GQRMR 71_ QGSIG 76_ AWRTI 81_ SPYLS 86_ GVGVA 91_ SVVVS 96_ FFLSM 101_ YYNVI 106_ NAWAF 111_ WYLFH 116_ SFQDP 121_ LPWSV 126_ CPLNG 131_ NHTGY 136_ DEECE 141_ KASST 146_ QYFWY 151_ RKTLN 156_ ISPSL 161_ QENGG 166_ VQWEP 171_ ALCLL 176_ LAWLV 181_ VYLCI 186_ LRGTE 191_ STGKV 196_ VYFTA 201_ SLPYC 206_ VLIIY 211_ LIRGL 216_ TLHGA 221_ TNGLM 226_ YMFTP 231_ KIEQL 236_ ANPKA 241_ WINAA 246_ TQIFF 251_ SLGLG 256_ FGSLI 261_ AFASY 266_ NEPSN 271_ NCQKH 276_ AIIVS 281_ LINSF 286_ TSIFA 291_ SIVTF 296_ SIYGF 301_ KATFN 306_ YENCL 311_ KKVSL 316_ LLTNT 321_ FDLED 326_ GFLTA 331_ SNLEQ 336_ VKGYL 341_ ASAYP 346_ SKYSE 351_ MFPQI 356_ KNCSL 361_ ESELD 366_ TAVQG 371_ TGLAF 376_ IVYTE 381_ AIKNM 386_ EVSQL 391_ WSVLY 396_ FFMLL 401_ MLGIG 406_ SMLGN 411_ TAAIL 416_ TPLTD 421_ SKIIS 426_ SHLPK 431_ EAISG 436_ LVCLV 441_ NCAIG 446_ MVFTM 451_ EAGNY 456_ WFDIF 461_ NDYAA 466_ TLSLL 471_ LIVLV 476_ ETIAV 481_ CYVYG 486_ LRRFE 491_ SDLKA 496_ MTGRA 501_ VSWYW 506_ KVMWA 511_ GVSPL 516_ LIVSL 521_ FVFYL 526_ SDYIL 531_ TGTLK 536_ YQAWD 541_ ASQGQ 546_ LVTKD 551_ YPAYA 556_ LAVIG 561_ LLVAS 566_ STMCI 571_ PLAAL 576_ GTFVQ 581_ RRLKR 586_GDADP
1: Mediates the Na(+)- and Cl(-)-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids (PubMed:15632147, PubMed:19033659, PubMed:33428810). Also transports glycine, regulates proline and glycine homeostasis in the brain playing a role in the modulation of NMDAR currents (PubMed:33428810)