Myozenin-2 (Calsarcin-1) (FATZ-related protein 2)
1_MLSHN 6_ TMMKQ 11_ RKQQA 16_ TAIMK 21_ EVHGN 26_ DVDGM 31_ DLGKK 36_ VSIPR 41_ DIMLE 46_ ELSHL 51_ SNRGA 56_ RLFKM 61_ RQRRS 66_ DKYTF 71_ ENFQY 76_ QSRAQ 81_ INHSI 86_ AMQNG 91_ KVDGS 96_ NLEGG 101_ SQQAP 106_ LTPPN 111_ TPDPR 116_ SPPNP 121_ DNIAP 126_ GYSGP 131_ LKEIP 136_ PEKFN 141_ TTAVP 146_ KYYQS 151_ PWEQA 156_ ISNDP 161_ ELLEA 166_ LYPKL 171_ FKPEG 176_ KAELP 181_ DYRSF 186_ NRVAT 191_ PFGGF 196_ EKASR 201_ MVKFK 206_ VPDFE 211_ LLLLT 216_ DPRFM 221_ SFVNP 226_ LSGRR 231_ SFNRT 236_ PKGWI 241_ SENIP 246_ IVITT 251_ EPTDD 256_TTVPE
1: Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis