Sperm-associated antigen 4 protein (Outer dense fiber-associated protein SPAG4) (SUN domain-containing protein 4)
1_MRRSS 6_ RPGSA 11_ SSSRK 16_ HTPNF 21_ FSENS 26_ SMSIT 31_ SEDSK 36_ GLRSA 41_ EPGPG 46_ EPEGR 51_ RARGP 56_ SCGEP 61_ ALSAG 66_ VPGGT 71_ TWAGS 76_ SQQKP 81_ APRSH 86_ NWQTA 91_ CGAAT 96_ VRGGA 101_ SEPTG 106_ SPVVS 111_ EEPLD 116_ LLPTL 121_ DLRQE 126_ MPPPR 131_ VFKSF 136_ LSLLF 141_ QGLSV 146_ LLSLA 151_ GDVLV 156_ SMYRE 161_ VCSIR 166_ FLFTA 171_ VSLLS 176_ LFLSA 181_ FWLGL 186_ LYLVS 191_ PLENE 196_ PKEML 201_ TLSEY 206_ HERVR 211_ SQGQQ 216_ LQQLQ 221_ AELDK 226_ LHKEV 231_ STVRA 236_ ANSER 241_ VAKLV 246_ FQRLN 251_ EDFVR 256_ KPDYA 261_ LSSVG 266_ ASIDL 271_ QKTSH 276_ DYADR 281_ NTAYF 286_ WNRFS 291_ FWNYA 296_ RPPTV 301_ ILEPH 306_ VFPGN 311_ CWAFE 316_ GDQGQ 321_ VVIQL 326_ PGRVQ 331_ LSDIT 336_ LQHPP 341_ PSVEH 346_ TGGAN 351_ SAPRD 356_ FAVFG 361_ LQVYD 366_ ETEVS 371_ LGKFT 376_ FDVEK 381_ SEIQT 386_ FHLQN 391_ DPPAA 396_ FPKVK 401_ IQILS 406_ NWGHP 411_ RFTCL 416_ YRVRA 421_ HGVRT 426_ SEGAE 431_GSAQG
1: Involved in spermatogenesis. Required for sperm head formation but not required to establish and maintain general polarity of the sperm head. Required for anchoring and organization of the manchette. Required for targeting of SUN3 and probably SYNE1 through a probable SUN1:SYNE3 LINC complex to the nuclear envelope and involved in accurate posterior sperm head localization of the complex. May anchor SUN3 the nuclear envelope. Involved in maintenance of the nuclear envelope integrity. May assist the organization and assembly of outer dense fibers (ODFs), a specific structure of the sperm tail