Inositol-3-phosphate synthase 1 (IPS 1) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase) (MI-1-P synthase) (MIP synthase) (hIPS) (Myo-inositol 1-phosphate synthase A1) (hINO1)
1_MEAAA 6_ QFFVE 11_ SPDVV 16_ YGPEA 21_ IEAQY 26_ EYRTT 31_ RVSRE 36_ GGVLK 41_ VHPTS 46_ TRFTF 51_ RTARQ 56_ VPRLG 61_ VMLVG 66_ WGGNN 71_ GSTLT 76_ AAVLA 81_ NRLRL 86_ SWPTR 91_ SGRKE 96_ ANYYG 101_ SLTQA 106_ GTVSL 111_ GLDAE 116_ GQEVF 121_ VPFSA 126_ VLPMV 131_ APNDL 136_ VFDGW 141_ DISSL 146_ NLAEA 151_ MRRAK 156_ VLDWG 161_ LQEQL 166_ WPHME 171_ ALRPR 176_ PSVYI 181_ PEFIA 186_ ANQSA 191_ RADNL 196_ IPGSR 201_ AQQLE 206_ QIRRD 211_ IRDFR 216_ SSAGL 221_ DKVIV 226_ LWTAN 231_ TERFC 236_ EVIPG 241_ LNDTA 246_ ENLLR 251_ TIELG 256_ LEVSP 261_ STLFA 266_ VASIL 271_ EGCAF 276_ LNGSP 281_ QNTLV 286_ PGALE 291_ LAWQH 296_ RVFVG 301_ GDDFK 306_ SGQTK 311_ VKSVL 316_ VDFLI 321_ GSGLK 326_ TMSIV 331_ SYNHL 336_ GNNDG 341_ ENLSA 346_ PLQFR 351_ SKEVS 356_ KSNVV 361_ DDMVQ 366_ SNPVL 371_ YTPGE 376_ EPDHC 381_ VVIKY 386_ VPYVG 391_ DSKRA 396_ LDEYT 401_ SELML 406_ GGTNT 411_ LVLHN 416_ TCEDS 421_ LLAAP 426_ IMLDL 431_ ALLTE 436_ LCQRV 441_ SFCTD 446_ MDPEP 451_ QTFHP 456_ VLSLL 461_ SFLFK 466_ APLVP 471_ PGSPV 476_ VNALF 481_ RQRSC 486_ IENIL 491_ RACVG 496_ LPPQN 501_ HMLLE 506_ HKMER 511_ PGPSL 516_ KRVGP 521_ VAATY 526_ PMLNK 531_ KGPVP 536_ AATNG 541_ CTGDA 546_ NGHLQ 551_EEPPM
1: Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner (PubMed:15024000, PubMed:23902760). Rate-limiting enzyme in the synthesis of all inositol-containing compounds (PubMed:15024000)