Mediator of RNA polymerase II transcription subunit 4 (Activator-recruited cofactor 36 kDa component) (ARC36) (Mediator complex subunit 4) (TRAP/SMCC/PC2 subunit p36 subunit) (Vitamin D3 receptor-interacting protein complex 36 kDa component) (DRIP36)
1_MAASS 6_ SGEKE 11_ KERLG 16_ GGLGV 21_ AGGNS 26_ TRERL 31_ LSALE 36_ DLEVL 41_ SRELI 46_ EMLAI 51_ SRNQK 56_ LLQAG 61_ EENQV 66_ LELLI 71_ HRDGE 76_ FQELM 81_ KLALN 86_ QGKIH 91_ HEMQV 96_ LEKEV 101_ EKRDS 106_ DIQQL 111_ QKQLK 116_ EAEQI 121_ LATAV 126_ YQAKE 131_ KLKSI 136_ EKARK 141_ GAISS 146_ EEIIK 151_ YAHRI 156_ SASNA 161_ VCAPL 166_ TWVPG 171_ DPRRP 176_ YPTDL 181_ EMRSG 186_ LLGQM 191_ NNPST 196_ NGVNG 201_ HLPGD 206_ ALAAG 211_ RLPDV 216_ LAPQY 221_ PWQSN 226_ DMSMN 231_ MLPPN 236_ HSSDF 241_ LLEPP 246_ GHNKE 251_ NEDDV 256_ EIMST 261_DSSSS
1: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors