Anoctamin-2 (Transmembrane protein 16B)
1_MATPG 6_ PRDIP 11_ LLPGS 16_ PRRLS 21_ PQAGS 26_ RGGQG 31_ PKHGQ 36_ QCLKM 41_ PGPRA 46_ PGLQG 51_ GSNRD 56_ PGQPC 61_ GGEST 66_ RSSSV 71_ INNYL 76_ DANEP 81_ VSLEA 86_ RLSRM 91_ HFHDS 96_ QRKVD 101_ YVLAY 106_ HYRKR 111_ GVHLA 116_ QGFPG 121_ HSLAI 126_ VSNGE 131_ TGKEP 136_ HAGGP 141_ GDIEL 146_ GPLDA 151_ LEEER 156_ KEQRE 161_ EFEHN 166_ LMEAG 171_ LELEK 176_ DLENK 181_ SQGSI 186_ FVRIH 191_ APWQV 196_ LAREA 201_ EFLKI 206_ KVPTK 211_ KEMYE 216_ IKAGG 221_ SIAKK 226_ FSAAL 231_ QKLSS 236_ HLQPR 241_ VPEHS 246_ NNKMK 251_ NLSYP 256_ FSREK 261_ MYLYN 266_ IQEKD 271_ TFFDN 276_ ATRSR 281_ IVHEI 286_ LKRTA 291_ CSRAN 296_ NTMGI 301_ NSLIA 306_ NNIYE 311_ AAYPL 316_ HDGEY 321_ DSPED 326_ DMNDR 331_ KLLYQ 336_ EWARY 341_ GVFYK 346_ FQPID 351_ LIRKY 356_ FGEKI 361_ GLYFA 366_ WLGLY 371_ TSFLI 376_ PSSVI 381_ GVIVF 386_ LYGCA 391_ TIEED 396_ IPSRE 401_ MCDQQ 406_ NAFTM 411_ CPLCD 416_ KSCDY 421_ WNLSS 426_ ACGTA 431_ QASHL 436_ FDNPA 441_ TVFFS 446_ IFMAL 451_ WATMF 456_ LENWK 461_ RLQMR 466_ LGYFW 471_ DLTGI 476_ EEEEE 481_ RAQEH 486_ SRPEY 491_ ETKVR 496_ EKMLK 501_ ESNQS 506_ AVQKL 511_ ETNTT 516_ ECGDE 521_ DDEDK 526_ LTWKD 531_ RFPGY 536_ LMNFA 541_ SILFM 546_ IALTF 551_ SIVFG 556_ VIVYR 561_ ITTAA 566_ ALSLN 571_ KATRS 576_ NVRVT 581_ VTATA 586_ VIINL 591_ VVILI 596_ LDEIY 601_ GAVAK 606_ WLTKI 611_ EVPKT 616_ EQTFE 621_ ERLIL 626_ KAFLL 631_ KFVNA 636_ YSPIF 641_ YVAFF 646_ KGRFV 651_ GRPGS 656_ YVYVF 661_ DGYRM 666_ EECAP 671_ GGCLM 676_ ELCIQ 681_ LSIIM 686_ LGKQL 691_ IQNNI 696_ FEIGV 701_ PKLKK 706_ LFRKL 711_ KDETE 716_ AGETD 721_ SAHSK 726_ HPEQW 731_ DLDYS 736_ LEPYT 741_ GLTPE 746_ YMEMI 751_ IQFGF 756_ VTLFV 761_ ASFPL 766_ APVFA 771_ LLNNV 776_ IEVRL 781_ DAKKF 786_ VTELR 791_ RPDAV 796_ RTKDI 801_ GIWFD 806_ ILSGI 811_ GKFSV 816_ ISNAF 821_ VIAIT 826_ SDFIP 831_ RLVYQ 836_ YSYSH 841_ NGTLH 846_ GFVNH 851_ TLSFF 856_ NVSQL 861_ KEGTQ 866_ PENSQ 871_ FDQEV 876_ QFCRF 881_ KDYRE 886_ PPWAP 891_ NPYEF 896_ SKQYW 901_ FILSA 906_ RLAFV 911_ IIFQN 916_ LVMFL 921_ SVLVD 926_ WMIPD 931_ IPTDI 936_ SDQIK 941_ KEKSL 946_ LVDFF 951_ LKEEH 956_ EKLKL 961_ MDEPA 966_ LRSPG 971_ GGDRS 976_ RSRAA 981_ SSAPS 986_ GQSQL 991_ GSMMS 996_SGSQH
1: Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina